Prkar1a - protein kinase cAMP-dependent type I regulatory subunit alpha Gene

Also Known as RIIA

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25725

Summary

Enables cAMP binding activity and cAMP-dependent protein kinase regulator activity. Involved in female meiotic nuclear division; negative regulation of meiotic nuclear division; and regulation of protein kinase activity. Located in cytoplasm. Part of cAMP-dependent protein kinase complex. Human ortholog(s) of this gene implicated in Carney complex; acrodysostosis; and primary pigmented nodular adrenocortical disease. Orthologous to human PRKAR1A (protein kinase cAMP-dependent type I regulatory subunit alpha). [provided by Alliance of Genome Resources, Apr 2022]

Prkar1a Products (1)

mRNA Protein Name
NM_013181.2 NP_037313.1 cAMP-dependent protein kinase type I-alpha regulatory subunit

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables cAMP binding IDA
IDA: Inferred from direct assay
11907174 RGD
enables cAMP-dependent protein kinase regulator activity IDA
IDA: Inferred from direct assay
11907174 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
17610895 RGD
Biological Process GO Annotation Evidence References Source
involved in female meiotic nuclear division IEP
IEP: Inferred from expression pattern
12088872 RGD
involved in negative regulation of meiotic nuclear division IEP
IEP: Inferred from expression pattern
12088872 RGD
involved in regulation of protein kinase activity IDA
IDA: Inferred from direct assay
11907174 RGD
Cellular Component GO Annotation Evidence References Source
part of cAMP-dependent protein kinase complex IDA
IDA: Inferred from direct assay
11907174 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cAMP-dependent protein kinase type I-alpha regulatory subunit

  • protein kinase cAMP-dependent type 1 regulatory subunit alpha

  • protein kinase, cAMP-dependent, regulatory subunit type I alpha

  • protein kinase, cAMP-dependent, regulatory, type I, alpha

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11112 PRKAR1A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17722 Prkar1a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24187 Prkar1a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Prkar1a NCBI NCBI:5573