Il2rb - interleukin 2 receptor subunit beta Gene

Also Known as IL2RBC

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25746

Summary

Enables interleukin-2 binding activity and interleukin-2 receptor activity. Involved in cytokine-mediated signaling pathway and natural killer cell activation. Located in cell surface. Human ortholog(s) of this gene implicated in asthma; immunodeficiency 63; myasthenia gravis; and visceral leishmaniasis. Orthologous to human IL2RB (interleukin 2 receptor subunit beta). [provided by Alliance of Genome Resources, Apr 2022]

Il2rb Products (1)

mRNA Protein Name
NM_013195.2 NP_037327.2 interleukin-2 receptor subunit beta precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables interleukin-2 binding IMP
IMP: Inferred from mutant phenotype
1469024 RGD
enables interleukin-2 receptor activity IMP
IMP: Inferred from mutant phenotype
1469024 RGD
Biological Process GO Annotation Evidence References Source
involved in cytokine-mediated signaling pathway IEP
IEP: Inferred from expression pattern
1889461 RGD
Cellular Component GO Annotation Evidence References Source
located in cell surface IDA
IDA: Inferred from direct assay
8898947 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

interleukin-2 receptor subunit beta

  • IL-2 receptor subunit beta

  • IL-2R subunit beta

  • IL-2RB

  • P70-75

  • high affinity IL-2 receptor subunit beta

  • interleukin 2 receptor, beta chain

Recombinant Il2rb Proteins

Cat. No. Product Name Accession Purity
HY-P76771 IL-2R beta/CD122 Protein, Rat (HEK293, His) NP_037327 (A27-E239) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P991279 Mik-Beta-1 Inhibitor ≥99.0% Phase 1

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06749 IL2RB Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16278 Il2rb Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17342 Il2rb Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Il2rb NCBI NCBI:3560