MXRA5 - matrix remodeling associated 5 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 25878

About MXRA5

Cytogenetic location: Xp22.33 Genomic coordinates (GRCh38): X:3,308,565-3,346,652 (from NCBI)

This gene has 1 transcript (splice variant), 202 orthologues and 36 paralogues. Ubiquitous expression in skin (RPKM 16.1), urinary bladder (RPKM 11.0) and 22 other tissues.

Summary

This gene encodes one of the matrix-remodelling associated proteins. This protein contains 7 leucine-rich repeats and 12 immunoglobulin-like C2-type domains related to perlecan. This gene has a pseudogene on chromosome Y. [provided by RefSeq, Mar 2010]

MXRA5 Products (1)

mRNA Protein Name
NM_015419.4 NP_056234.2 matrix-remodeling-associated protein 5 precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in response to transforming growth factor beta IMP
IMP: Inferred from mutant phenotype
27599751 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

MXRA5 Protein Structure

LRR_8

LRR_8: Leucine rich repeat (111 - 163)

I-set

I-set: Immunoglobulin I-set domain (487 - 560)

I-set

I-set: Immunoglobulin I-set domain (590 - 668)

I-set

I-set: Immunoglobulin I-set domain (1857 - 1944)

I-set

I-set: Immunoglobulin I-set domain (1956 - 2042)

I-set

I-set: Immunoglobulin I-set domain (2052 - 2139)

I-set

I-set: Immunoglobulin I-set domain (2151 - 2238)

I-set

I-set: Immunoglobulin I-set domain (2251 - 2341)

I-set

I-set: Immunoglobulin I-set domain (2355 - 2434)

I-set

I-set: Immunoglobulin I-set domain (2458 - 2535)

I-set

I-set: Immunoglobulin I-set domain (2549 - 2633)

Ig_2

Ig_2: Immunoglobulin domain (2648 - 2726)

I-set

I-set: Immunoglobulin I-set domain (2733 - 2826)

  • 0
  • 500
  • 1000
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  • 2500
  • 2828 a.a.
Protein Preferred Names Protein Names

matrix-remodeling-associated protein 5

  • adhesion protein with leucine-rich repeats and Immunoglobulin domains related to perlecan

Related Diseases

Diseases Alias
Lung Cancer

  • Lung Carcinoma

  • Non-Small Cell Lung Carcinoma

  • Lung Cancer, Susceptibility To

  • Lung Cancer, Protection Against

  • Adenocarcinoma Of Lung, Somatic

  • Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In

  • Nonsmall Cell Lung Cancer

  • Lung Neoplasm

  • Carcinoma Of Lung

  • Lung Non-Small Cell Carcinoma

  • Non-Small Cell Lung Cancer

  • Nsclc

  • Lung Neoplasms

  • Malignant Neoplasm Of Lung

  • Alveolar Cell Carcinoma

  • Nonsmall Cell Lung Cancer, Somatic

  • Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In

  • Nonsmall Cell Lung Cancer, Susceptibility To

  • Lung Cancer, Somatic

  • Lung Cancer, Resistance To

  • Cancer Of Lung

  • Cancer Of Bronchus

  • Cancer Of The Lung

  • Lung Malignancies

  • Lung Malignant Tumors

  • Malignant Lung Tumor

  • Malignant Tumor Of Lung

  • Pulmonary Cancer

  • Pulmonary Carcinoma

  • Pulmonary Neoplasms

  • Respiratory Carcinoma

  • LNCR

  • Adenocarcinoma Of Lung

  • Neoplasm Of Lung

  • Cancer Lung

  • Carcinoma Non-Small Cell Lung

  • Carcinoma, Non-Small-Cell Lung

  • Lung Cancers

  • Lung Carcinomas

  • Cancer, Lung

  • Cancer, Lung, Non-Small Cell

  • Primary Malignant Neoplasm Of Lung

  • Bronchioloalveolar Adenocarcinoma
Autosomal Dominant Polycystic Kidney Disease

  • Polycystic Kidney Disease, Adult Type

  • Adpkd

  • Polycystic Kidney Diseases

  • Polycystic Kidney, Autosomal Dominant

  • Congenital Biliary Ectasias

  • Polycystic Kidney And Hepatic Disease 1

  • Polycystic Kidney Disease, Autosomal Dominant

  • Kidney, Polycystic, Disease, Autosomal Dominant

  • Adult Polycystic Kidney Disease

  • Polycystic Kidney, Adult Type

  • Apckd - [Autosomal Polycystic Kidney Disease]
Phosphoglycerate Dehydrogenase Deficiency

  • Phgdh Deficiency

  • 3-Phosphoglycerate Dehydrogenase Deficiency

  • PHGDHD

  • 3-Pgdh Deficiency

  • 3-Phosphoglycerate Dehydrogenase Deficiency, Infantile/Juvenile Form

  • Phgdh Deficiency, Infantile/Juvenile Form

  • Deficiency, Phosphoglycerate Dehydrogenase
Chronic Kidney Disease

  • Chronic Renal Disease

  • Chronic Kidney Failure

  • Ckd

  • Chronic Renal Failure

  • Kidney Failure, Chronic

  • Chronic Renal Failure Syndrome

  • Crf

  • Renal Failure - Chronic

  • Renal Failure Chronic

  • Chronic Kidney Diseases

  • Chronic Kidney Disease Stage 5

  • Ckd - [Chronic Kidney Disease]

  • Crf - [Chronic Renal Failure]

  • Chronic Kidney Impairment

  • Chronic Renal Impairment

  • Chronic Kidney Shutdown

  • Chronic Hypoxic Kidney Failure

  • Chronic Kidney Collapse

  • Chronic Renal Insufficiency

  • Chronic Kidney Toxaemia

  • Chronic Kidney Hypofunction

  • Chronic Renal Suppression

  • Chronic Renal Failure, Stage 5

  • Ckd - [Chronic Kidney Disease] Stage 5

  • End Stage Kidney Failure

  • End Stage Renal Failure

  • End Stage Kidney Disease

  • End Stage Renal Disease

  • End Stage Chronic Renal Failure

  • Esrf - [End Stage Renal Failure]

  • Esrd - [End Stage Renal Diseases]

  • Egfr - [Estimated Glomerular Filtration Rate] < 15 Ml/Min/1.73m²
Polycystic Kidney Disease

  • Polycystic Kidney Diseases

  • Pkd

  • Polycystic Renal Disease

  • Kidney Disease, Polycystic

  • Polycystic Kidney, Autosomal Dominant
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08865 MXRA5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown