Grk6 - G protein-coupled receptor kinase 6 Gene

Also Known as Gprk6

Species: Mus musculus

Gene Type: protein coding
Gene ID: 26385

Summary

Enables protein kinase activity. Involved in protein phosphorylation. Predicted to be located in cytosol. Predicted to be active in cytoplasm and plasma membrane. Is expressed in several structures, including genitourinary system; liver; lung; spleen; and submandibular gland primordium. Human ortholog(s) of this gene implicated in Parkinson's disease. Orthologous to human GRK6 (G protein-coupled receptor kinase 6). [provided by Alliance of Genome Resources, Apr 2022]

Grk6 Products (9)

mRNA Protein Name
NM_001038018.5 NP_001033107.1 G protein-coupled receptor kinase 6 isoform a
NM_001112711.2 NP_001106182.1 G protein-coupled receptor kinase 6 isoform c
NM_001286063.2 NP_001272992.1 G protein-coupled receptor kinase 6 isoform d
NM_001286064.2 NP_001272993.1 G protein-coupled receptor kinase 6 isoform e
NM_001286065.1 NP_001272994.1 G protein-coupled receptor kinase 6 isoform f
NM_001286066.2 NP_001272995.1 G protein-coupled receptor kinase 6 isoform g
NM_001377076.1 NP_001364005.1 G protein-coupled receptor kinase 6 isoform h
NM_001377077.1 NP_001364006.1 G protein-coupled receptor kinase 6 isoform i
NM_011938.5 NP_036068.2 G protein-coupled receptor kinase 6 isoform b

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
10446210 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

G protein-coupled receptor kinase 6

  • g protein-coupled receptor kinase GRK6

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-142817 GRK6/Aurora A-IN-1 Inhibitor 98.98% Unkown
HY-180583 GRK5-IN-5 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Grk6 NCBI NCBI:2870