Poli - polymerase (DNA directed), iota Gene

Also Known as Rad30b

Species: Mus musculus

Gene Type: protein coding
Gene ID: 26447

Summary

Enables DNA-directed DNA Polymerase activity. Acts upstream of or within cellular response to UV-C and translesion synthesis. Predicted to be located in cytoplasmic ribonucleoprotein granule and nuclear speck. Is expressed in brain; metanephros; primary spermatocyte; spermatid; and testis. Orthologous to human POLI (DNA Polymerase iota). [provided by Alliance of Genome Resources, Apr 2022]

Poli Products (13)

mRNA Protein Name
NM_001136090.3 NP_001129562.1 DNA polymerase iota isoform 1
NM_001289516.2 NP_001276445.1 DNA polymerase iota isoform 4
NM_001403167.1 NP_001390096.1 DNA polymerase iota isoform 6 (long)
NM_001403168.1 NP_001390097.1 DNA polymerase iota isoform 5 (long)
NM_001403169.1 NP_001390098.1 DNA polymerase iota isoform 6 (short)
NM_001403173.1 NP_001390102.1 DNA polymerase iota isoform 5 (short)
NM_001403174.1 NP_001390103.1 DNA polymerase iota isoform 8
NM_001403175.1 NP_001390104.1 DNA polymerase iota isoform 7
NM_001403177.1 NP_001390106.1 DNA polymerase iota isoform 8
NM_001403179.1 NP_001390108.1 DNA polymerase iota isoform 7
NM_001403183.1 NP_001390112.1 DNA polymerase iota isoform 1
NM_001403189.1 NP_001390118.1 DNA polymerase iota isoform 2 (short)
NM_011972.3 NP_036102.2 DNA polymerase iota isoform 2 (long)

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables DNA-directed DNA polymerase activity IDA
IDA: Inferred from direct assay
12925679 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within cellular response to UV-C IGI
IGI: Inferred from genetic interaction
17114294 MGI
acts upstream of or within cellular response to UV-C IMP
IMP: Inferred from mutant phenotype
17114294 MGI
acts upstream of or within translesion synthesis IMP
IMP: Inferred from mutant phenotype
17114294 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

DNA polymerase iota

  • RAD30 homolog B

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-121678 Tetridamine 99.79% Unkown
HY-RS10832 POLI Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17247 Poli Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23701 Poli Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Poli NCBI NCBI:11201