Ccnb1 - cyclin B1 Gene

Also Known as CycB1; Cycb-4; Cycb-5; Ccnb1-rs1; Cycb1-rs1; Ccnb1-rs13

Species: Mus musculus

Gene Type: protein coding
Gene ID: 268697

Summary

Predicted to enable cyclin-dependent protein serine/threonine kinase activator activity; enzyme binding activity; and patched binding activity. Acts upstream of or within several processes, including histone H3-S10 phosphorylation involved in chromosome condensation; in utero embryonic development; and positive regulation of fibroblast proliferation. Located in cytoplasm; membrane; and nucleus. Colocalizes with mitochondrial matrix. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; eye; and genitourinary system. Human ortholog(s) of this gene implicated in breast Cancer and prostate Cancer. Orthologous to human CCNB1 (cyclin B1). [provided by Alliance of Genome Resources, Apr 2022]

Ccnb1 Products (1)

mRNA Protein Name
NM_172301.3 NP_758505.2 G2/mitotic-specific cyclin-B1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
12124778 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within in utero embryonic development IMP
IMP: Inferred from mutant phenotype
9539739 MGI
acts upstream of or within positive regulation of cell cycle IDA
IDA: Inferred from direct assay
22053081 MGI
acts upstream of or within positive regulation of fibroblast proliferation IMP
IMP: Inferred from mutant phenotype
22053081 MGI
acts upstream of or within protein phosphorylation IDA
IDA: Inferred from direct assay
12124778 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
17325031 MGI
located in membrane IDA
IDA: Inferred from direct assay
9539739 MGI
colocalizes with mitochondrial matrix IDA
IDA: Inferred from direct assay
24746669 MGI
located in nucleus IDA
IDA: Inferred from direct assay
14993286 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

G2/mitotic-specific cyclin-B1

  • cyclin B1, related sequence 1

  • cyclin B1, related sequence 13

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (10)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-114779 N9-Isopropylolomoucine Inhibitor 99.34% Unkown
HY-RS02118 CCNB1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-162895 NL13 / Unkown
HY-181076 FOXM1-IN-3 / Unkown
HY-181769 Anticancer agent 306 / Unkown
HY-P11028 M1-20 Inhibitor / Unkown
HY-RS02119 CCNB1IP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-N19821 Gangaleoidin Inhibitor / Unkown
HY-RS17545 Ccnb1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24004 Ccnb1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ccnb1 NCBI NCBI:891