CADPS - Cadps calcium dependent secretion activator Gene

Also Known as Caps; Caps1; Caps2

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 26989

Summary

Enables calcium ion binding activity and phosphatidylinositol-4,5-bisphosphate binding activity. Involved in positive regulation of calcium ion-dependent exocytosis. Located in dense core granule. Is active in glutamatergic synapse and presynapse. Is extrinsic component of neuronal dense core vesicle membrane. Orthologous to human CADPS (calcium dependent secretion activator). [provided by Alliance of Genome Resources, Apr 2022]

CADPS Products (1)

mRNA Protein Name
NM_013219.2 NP_037351.2 calcium-dependent secretion activator 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables calcium ion binding IDA
IDA: Inferred from direct assay
9289490 RGD
enables phosphatidylinositol-4,5-bisphosphate binding IDA
IDA: Inferred from direct assay
9525942 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
19805029 RGD
Biological Process GO Annotation Evidence References Source
involved in positive regulation of calcium ion-dependent exocytosis IMP
IMP: Inferred from mutant phenotype
9289490 RGD
involved in positive regulation of exocytosis IMP
IMP: Inferred from mutant phenotype
24356451 RGD
Cellular Component GO Annotation Evidence References Source
located in dense core granule IDA
IDA: Inferred from direct assay
24356451 RGD
is active in extrinsic component of neuronal dense core vesicle membrane IDA
IDA: Inferred from direct assay
9697858 RGD
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
14530279 RGD
is active in presynapse IDA
IDA: Inferred from direct assay
14530279 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

calcium-dependent secretion activator 1

  • CAPS-1

  • Ca++-dependent secretion activator

  • Ca2+ dependent secretion activator

  • Ca2+-dependent activator protein

  • Ca<2+-dependent activator protein for secretion

  • calcium-dependent activator protein for secretion 1

  • calcium-dependent secretion activator 1

CADPS Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Cadps Q62717 Stx1a Rattus norvegicus P32851
Density Sedimentation
19805029
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01823 CADPS Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS01824 CADPS2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens CADPS NCBI NCBI:8618