G3bp1 - GTPase activating protein (SH3 domain) binding protein 1 Gene

Also Known as G3bp; mKIAA4115; B430204O07

Species: Mus musculus

Gene Type: protein coding
Gene ID: 27041

Summary

Enables mRNA binding activity. Acts upstream of or within negative regulation of canonical Wnt signaling pathway. Located in cytoplasmic stress granule. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human G3BP1 (G3BP stress granule assembly factor 1). [provided by Alliance of Genome Resources, Apr 2022]

G3bp1 Products (1)

mRNA Protein Name
NM_013716.2 NP_038744.1 ras GTPase-activating protein-binding protein 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables mRNA binding IDA
IDA: Inferred from direct assay
21652632 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
21652632 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within negative regulation of canonical Wnt signaling pathway IMP
IMP: Inferred from mutant phenotype
21652632 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasmic stress granule IDA
IDA: Inferred from direct assay
18625844 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ras GTPase-activating protein-binding protein 1

  • ATP-dependent DNA helicase VIII

  • G3BP-1

  • GAP SH3 binding protein

  • GAP SH3 domain-binding protein 1

  • HDH-VIII

  • Ras-GTPase-activating protein SH3-domain binding protein 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (8)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-162288 FAZ-3532 Inhibitor 99.66% Unkown
HY-162289 FAZ-3780 99.68% Unkown
HY-170872 PT-129 98.66% Unkown
HY-RS05189 G3BP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-124072 HL001 98.90% Unkown
HY-170873 G3BP1/2-Targeting ligand-1 Ligand 99.61% Unkown
HY-RS17909 G3bp1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24378 G3bp1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens G3bp1 NCBI NCBI:10146