IL17C - interleukin 17C Gene

Homo sapiens

Also known as CX2; IL-17C

Gene ID: 27189 | Gene type: protein coding

About IL17C

Cytogenetic location: 16q24.2 Genomic coordinates (GRCh38): 16:88,638,572-88,640,468 (from NCBI)

This gene has 2 transcripts (splice variants), 186 orthologues and 5 paralogues. Biased expression in endometrium (RPKM 1.7), gall bladder (RPKM 0.2) and 1 other tissue.

Summary

The protein encoded by this gene is a T cell-derived cytokine that shares the sequence similarity with IL17. This cytokine was reported to stimulate the release of tumor necrosis factor alpha and interleukin 1 beta from a monocytic cell line. The expression of this cytokine was found to be restricted to activated T cells. [provided by RefSeq, Jul 2008]

IL17C Products(1)

mRNA	Protein	Name
NM_013278.4	NP_037410.1	interleukin-17C precursor

IL17C Protein Structure

IL17

0
100
197 a.a.

Protein Preferred Names

Protein Names

interleukin-17C

cytokine CX2

Recombinant IL17C Proteins

Cat. No.	Product Name	Accession	Purity
HY-P72383	IL-17C Protein, Human (Biotinylated, HEK293, His-Avi)	Q9P0M4 (H19-V197)	≥95%
HY-P72587	IL-17C Protein, Human (HEK293, His)	Q9P0M4 (H19-V197)	≥95%
HY-P75836	IL-17C Protein, Human (sf9, Fc)	Q9P0M4 (M1-V197)	≥95%
HY-P78469	IL-17C Protein, Human (HEK293, His-Avi)	Q9P0M4 (H19-V197)	≥95%

Related Diseases

Diseases

Alias

Anal Gland Neoplasm

Anal Gland Neoplasms

Cutaneous Candidiasis

Candidiasis, Cutaneous

Non-Syndromic X-Linked Intellectual Disability 89

Mrx89

Pustulosis Of Palm And Sole

Psoriasis	Acropustulosis
Palmoplantar Pustulosis	Pustular Psoriasis Of The Palms And/Or Soles
Pustulosis Of Palms And Soles	Acrodermatitis Continua Of Hallopeau
Generalized Pustular Psoriasis

Septal Myocardial Infarction

Mental Retardation, X-Linked 92

MRX92	Intellectual Developmental Disorder, X-Linked 92
Non-Syndromic X-Linked Intellectual Disability 92	X-Linked Mental Retardation 92
Mental Retardation, X-Linked, Type 92

Chlorhexidine Allergy

Autoimmune Disease Of Skin And Connective Tissue

Chronic Mucocutaneous Candidiasis

Candidiasis, Chronic Mucocutaneous	Cmc
Candidiasis Chronic Mucocutaneous

Systemic Lupus Erythematosus

Lupus Nephritis	SLE
Disseminated Lupus Erythematosus	Systemic Lupus Erythematosus, Susceptibility To
Lupus Erythematosus, Systemic	Lupus Nephritis, Susceptibility To
Libman-Sacks Disease	Systemic Lupus Erythematosus Susceptibility To
Sle - Lupus Erythematosus, Systemic	Le Syndrome
Lupus	Lupus Erythematosus Systemic
Lupus Erythematosus, Systemic, Susceptibility To	Lupus Vulgaris
Lupus Erythematosus, Discoid	Lupus Erythematosus
Systemic Lupus Erythematosus Nos	Sle - [Systemic Lupus Erythematosus]

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P5963	Lib2-1	Inhibitor	/	Unkown
HY-RS06699	IL17C Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	IL17C	RGD	RGD:1582798
Mus musculus	IL17C	MGD	MGI:2446486
Bos taurus	IL17C	VGNC	VGNC:30119
Canis familiaris	IL17C	VGNC	VGNC:41944
Others	IL17C	NCBI

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