Pla2g7 - phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) Gene

Also Known as PAF-AH

Species: Mus musculus

Gene Type: protein coding
Gene ID: 27226

Summary

Predicted to enable 1-alkyl-2-acetylglycerophosphocholine esterase activity; calcium-independent Phospholipase A2 activity; and phospholipid binding activity. Predicted to be involved in several processes, including glycerophospholipid catabolic process; plasma lipoprotein particle remodeling; and positive regulation of monocyte chemotaxis. Predicted to act upstream of or within inflammatory response. Predicted to be located in cytoplasm and extracellular space. Predicted to be part of high-density lipoprotein particle and low-density lipoprotein particle. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); glomerulonephritis (multiple); hemolytic-uremic syndrome; proteinuria (multiple); and type 2 diabetes mellitus. Orthologous to human PLA2G7 (Phospholipase A2 group VII). [provided by Alliance of Genome Resources, Apr 2022]

Pla2g7 Products (1)

mRNA Protein Name
NM_013737.5 NP_038765.2 platelet-activating factor acetylhydrolase precursor
Protein Preferred Names Protein Names

platelet-activating factor acetylhydrolase

  • 1-alkyl-2-acetylglycerophosphocholine esterase

  • 2-acetyl-1-alkylglycerophosphocholine esterase

  • LDL-PLA(2)

  • LDL-associated phospholipase A2

  • PAF 2-acylhydrolase

  • PAF acetylhydrolase

Recombinant Pla2g7 Proteins

Cat. No. Product Name Accession Purity
HY-P77444 PLA2G7 Protein, Mouse (HEK293, His) Q60963/NP_038765.2 (F22-N440) ≥ 90%, as determined by reducing SDS-PAGE.
HY-P700567 PLA2G7 Protein, Mouse (sf9, His, Myc) Q60963 (F22-N440) ≥ 90%, as determined by reducing SDS-PAGE.
HY-P700568 PLA2G7 Protein, Mouse (HEK293, His, Myc) Q60963 (F22-N440) ≥ 90%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-18540 KT109 Inhibitor 99.86% Unkown
HY-RS10634 PLA2G7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16659 Pla2g7 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23094 Pla2g7 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pla2g7 NCBI NCBI:7941