Atf5 - activating transcription factor 5 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 282840

Summary

Enables several functions, including DNA-binding transcription factor activity; chromatin binding activity; and heat shock protein binding activity. Involved in negative regulation of apoptotic process; negative regulation of astrocyte differentiation; and positive regulation of transcription, DNA-templated. Located in nucleus. Orthologous to human ATF5 (activating transcription factor 5). [provided by Alliance of Genome Resources, Apr 2022]

Atf5 Products (1)

mRNA Protein Name
NM_172336.4 NP_758839.3 cyclic AMP-dependent transcription factor ATF-5

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables DNA-binding transcription factor activity IDA
IDA: Inferred from direct assay
19531563 RGD
enables chromatin binding IDA
IDA: Inferred from direct assay
21212266 RGD
enables heat shock protein binding IPI
IPI: Inferred from physical interaction
21521685 RGD
enables sequence-specific DNA binding IDA
IDA: Inferred from direct assay
19531563 RGD
enables transcription cis-regulatory region binding IDA
IDA: Inferred from direct assay
19531563 RGD
Biological Process GO Annotation Evidence References Source
involved in negative regulation of apoptotic process IMP
IMP: Inferred from mutant phenotype
21212266 RGD
involved in negative regulation of astrocyte differentiation IMP
IMP: Inferred from mutant phenotype
15829641 RGD
involved in negative regulation of neurogenesis IDA
IDA: Inferred from direct assay
12805299 RGD
involved in positive regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
19531563 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cyclic AMP-dependent transcription factor ATF-5

  • cAMP-dependent transcription factor ATF-5

  • transcription factor ATFx

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-112680A Carboxy pyridostatin trifluoroacetate salt 99.49% Unkown
HY-112680 Carboxypyridostatin 99.41% Unkown
HY-RS19118 Atf5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS01131 ATF5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25608 Atf5 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Atf5 NCBI NCBI:22809