Parl - presenilin associated, rhomboid-like Gene
Also Known as Psarl
Species: Rattus norvegicus
Gene Type: protein coding
Gene ID: 287979
Summary
Predicted to enable serine-type endopeptidase activity. Involved in neuron differentiation and response to nutrient levels. Located in mitochondrion and nucleus. Human ortholog(s) of this gene implicated in Leber hereditary optic neuropathy; coronary artery disease; hyperinsulinism; myopia; and type 2 diabetes mellitus. Orthologous to human PARL (presenilin associated rhomboid like). [provided by Alliance of Genome Resources, Apr 2022]
Parl Products (2)
| mRNA | Protein | Name |
|---|---|---|
| NM_001035249.1 | NP_001030326.1 | presenilins-associated rhomboid-like protein, mitochondrial precursor |
| NM_001035249.1 | NP_001030326.1 | presenilins-associated rhomboid-like protein, mitochondrial precursor |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
presenilins-associated rhomboid-like protein, mitochondrial |
|
Related Agents
- Clinical Phase
- Pre-clinical Phase
Clinical Phase
Bioactive Molecules
(1)
| Cat. No. | Product Name |
Effect
|
Purity |
Phase
|
|---|---|---|---|---|
| HY-152265A | PARL-IN-1 TFA | Activator | / | Phase 2 |
Pre-clinical Phase
Bioactive Molecules
(5)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-169380 | PARL-IN-2 | 99.80% | Unkown | |
| HY-152265 | PARL-IN-1 | Activator | 96.57% | Unkown |
| HY-RS10044 | PARL Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS18365 | Parl Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS24844 | Parl Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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