Mylk - myosin light chain kinase Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 288057

Summary

Predicted to enable enzyme binding activity and Myosin light chain kinase activity. Predicted to be involved in several processes, including aorta smooth muscle tissue morphogenesis; bleb assembly; and cellular hypotonic response. Predicted to act upstream of or within cellular response to calcium ion; cellular response to potassium ion; and cellular response to xenobiotic stimulus. Predicted to be located in actin cytoskeleton; cell-cell junction; and plasma membrane. Predicted to be active in several cellular components, including cleavage furrow; lamellipodium; and stress fiber. Human ortholog(s) of this gene implicated in adult respiratory distress syndrome; asthma; and thoracic aortic aneurysm. Orthologous to human MYLK (Myosin light chain kinase). [provided by Alliance of Genome Resources, Apr 2022]

Mylk Products (1)

mRNA Protein Name
NM_001105874.2 NP_001099344.2 myosin light chain kinase, smooth muscle

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in regulation of synaptic vesicle endocytosis EXP
EXP: Inferred from Experiment
27062289 RGD
involved in regulation of synaptic vesicle endocytosis IDA
IDA: Inferred from direct assay
27062289 RGD
involved in regulation of synaptic vesicle endocytosis IMP
IMP: Inferred from mutant phenotype
27062289 RGD
Cellular Component GO Annotation Evidence References Source
is active in synapse IDA
IDA: Inferred from direct assay
17093082 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

myosin light chain kinase, smooth muscle

  • myosin, light polypeptide kinase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (11)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-176882 ASK1-IN-11 Inhibitor / Unkown
HY-RS08923 MYLK Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS08924 MYLK2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS08925 MYLK3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS08926 MYLK4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18624 Mylk Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22661 Mylk3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22662 Mylk4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25110 Mylk Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29175 Mylk3 Rat Pre-designed siRNA Set A / Unkown
HY-RS29176 Mylk4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mylk NCBI NCBI:4638