2. Gene
  3. Pik3c2b - phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta Gene

Pik3c2b - phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 289021 | Gene type: protein coding

About Pik3c2b

Primary_assembly 13: 44,495,050-44,555,612 forward strand.mRatBN7.2:CM026986.1

This gene has 2 transcripts (splice variants), 207 orthologues, 9 paralogues and is associated with 4 phenotypes. Biased expression in Heart (RPKM 69.9), Muscle (RPKM 58.1) and 9 other tissues.

Summary

Predicted to enable 1-phosphatidylinositol-3-kinase activity; 1-phosphatidylinositol-4-phosphate 3-kinase activity; and lipid kinase activity. Predicted to be involved in cell migration; phosphatidylinositol 3-kinase signaling; and phosphatidylinositol-3-phosphate biosynthetic process. Predicted to act upstream of or within autophagosome organization; cellular response to starvation; and protein kinase B signaling. Predicted to be located in cytosol; endocytic vesicle; and nucleoplasm. Predicted to be part of phosphatidylinositol 3-kinase complex. Predicted to be active in cytoplasm and plasma membrane. Orthologous to human PIK3C2B (phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta). [provided by Alliance of Genome Resources, Apr 2022]

Pik3c2b Products(1)

mRNA Protein Name
NM_001105951.1 NP_001099421.1 phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta

Pik3c2b Protein Structure

PI3K_rbd

PI3K_rbd: pfam00794 (362 - 464)

C2A_PI3K_class_II

C2A_PI3K_class_II: cd04012 (620 - 792)

PI3Ka_II

PI3Ka_II: cd00869 (811 - 979)

PI3Kc_C2_beta

PI3Kc_C2_beta: cd00895 (985 - 1338)

PX_PI3K_C2_beta

PX_PI3K_C2_beta: cd07290 (1367 - 1475)

C2B_PI3K_class_II

C2B_PI3K_class_II: cd08381 (1503 - 1625)

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  • 1633 a.a.
Protein Preferred Names Protein Names

phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta

nuclear cap binding protein subunit 2

phosphoinositide-3-kinase, class 2, beta polypeptide

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-112608 CHMFL-PI3KD-317 Inhibitor 98.04% Unkown
HY-RS10514 PIK3C2B Human Pre-designed siRNA Set A / Unkown
HY-RS10515 Pik3c2b Mouse Pre-designed siRNA Set A / Unkown
HY-RS10516 Pik3c2b Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pik3c2b NCBI NCBI:5287