Pik3c2b - phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta Gene
Species: Rattus norvegicus
About Pik3c2b
This gene has 2 transcripts (splice variants), 207 orthologues, 9 paralogues and is associated with 4 phenotypes. Biased expression in Heart (RPKM 69.9), Muscle (RPKM 58.1) and 9 other tissues.
Summary
Predicted to enable 1-phosphatidylinositol-3-kinase activity; 1-phosphatidylinositol-4-phosphate 3-kinase activity; and lipid kinase activity. Predicted to be involved in cell migration; phosphatidylinositol 3-kinase signaling; and phosphatidylinositol-3-phosphate biosynthetic process. Predicted to act upstream of or within autophagosome organization; cellular response to starvation; and protein kinase B signaling. Predicted to be located in cytosol; endocytic vesicle; and nucleoplasm. Predicted to be part of phosphatidylinositol 3-kinase complex. Predicted to be active in cytoplasm and plasma membrane. Orthologous to human PIK3C2B (phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta). [provided by Alliance of Genome Resources, Apr 2022]
Pik3c2b Products (2)
| mRNA | Protein | Name |
|---|---|---|
| NM_001105951.1 | NP_001099421.1 | phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta |
| NM_001105951.1 | NP_001099421.1 | phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta |
Pik3c2b Protein Structure
PI3K_rbd: pfam00794 (362 - 464)
C2A_PI3K_class_II: cd04012 (620 - 792)
PI3Ka_II: cd00869 (811 - 979)
PI3Kc_C2_beta: cd00895 (985 - 1338)
PX_PI3K_C2_beta: cd07290 (1367 - 1475)
C2B_PI3K_class_II: cd08381 (1503 - 1625)
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- 1633 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta |
|