Vangl2 - VANGL planar cell polarity protein 2 Gene

Also Known as Ltap

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 289229

Summary

Predicted to be involved in axon guidance; cell migration involved in kidney development; and morphogenesis of an epithelium. Predicted to act upstream of or within several processes, including animal organ development; morphogenesis of an epithelium; and regulation of signal transduction. Predicted to be located in several cellular components, including basolateral plasma membrane; lateral plasma membrane; and stress fiber. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in neural tube defect. Orthologous to human VANGL2 (VANGL planar cell polarity protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Vangl2 Products (1)

mRNA Protein Name
NM_001105969.1 NP_001099439.1 vang-like protein 2

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
26257100 RGD
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
26257100 RGD
is active in postsynaptic density membrane IDA
IDA: Inferred from direct assay
26257100 RGD
is active in postsynaptic density membrane IMP
IMP: Inferred from mutant phenotype
26257100 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

vang-like protein 2

  • loop tail associated protein

  • van Gogh-like protein 2

  • vang-like 2 (van gogh, Drosophila)

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15601 VANGL2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21218 Vangl2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27734 Vangl2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Vangl2 NCBI NCBI:57216