Mbd1 - methyl-CpG binding domain protein 1 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 291439

Summary

Enables chromatin binding activity. Involved in several processes, including generation of neurons; response to cocaine; and response to estradiol. Located in chromatin; cytoplasm; and nucleus. Biomarker of transient cerebral ischemia and visual epilepsy. Human ortholog(s) of this gene implicated in lung Cancer. Orthologous to human MBD1 (methyl-CpG binding domain protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Mbd1 Products (1)

mRNA Protein Name
NM_001011924.1 NP_001011924.1 methyl-CpG-binding domain protein 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables chromatin binding IDA
IDA: Inferred from direct assay
18689796 RGD
Biological Process GO Annotation Evidence References Source
involved in epigenetic regulation of gene expression IEP
IEP: Inferred from expression pattern
20735989 RGD
involved in negative regulation of astrocyte differentiation IDA
IDA: Inferred from direct assay
16881068 RGD
involved in negative regulation of gene expression IDA
IDA: Inferred from direct assay
16881068 RGD
involved in neuron differentiation IEP
IEP: Inferred from expression pattern
19660178 RGD
involved in response to cocaine IEP
IEP: Inferred from expression pattern
16670375 RGD
involved in response to estradiol IEP
IEP: Inferred from expression pattern
22109888 RGD
involved in response to nutrient levels IEP
IEP: Inferred from expression pattern
16702315 RGD
involved in response to organic cyclic compound IEP
IEP: Inferred from expression pattern
22109888 RGD
involved in response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
16670375 RGD
involved in ventricular cardiac muscle tissue development IEP
IEP: Inferred from expression pattern
20735989 RGD
Cellular Component GO Annotation Evidence References Source
located in chromatin IDA
IDA: Inferred from direct assay
18689796 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

methyl-CpG-binding domain protein 1

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-159978 EOS789 Inhibitor 99.14% Phase 1

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03947 DPEP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS08181 MBD1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22228 Mbd1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28750 Mbd1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mbd1 NCBI NCBI:4152