Ctbp1 - C-terminal binding protein 1 Gene

Also Known as Bars; BARS-50; CtBP3/BARS; 50-kDaBFA-inducedADP-ribosylatedsubstrate

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29382

Summary

Enables NAD binding activity; PDZ domain binding activity; and protein homodimerization activity. Involved in presynapse to nucleus signaling pathway. Located in cytoplasm; nucleus; and presynapse. Is active in glutamatergic synapse. Orthologous to human CTBP1 (C-terminal binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Ctbp1 Products (1)

mRNA Protein Name
NM_019201.3 NP_062074.2 C-terminal-binding protein 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables NAD binding IDA
IDA: Inferred from direct assay
19351597 RGD
enables PDZ domain binding IPI
IPI: Inferred from physical interaction
11590170 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
12372828 RGD
enables protein homodimerization activity IPI
IPI: Inferred from physical interaction
19351597 RGD
Biological Process GO Annotation Evidence References Source
involved in presynapse to nucleus signaling pathway IDA
IDA: Inferred from direct assay
25652077 RGD
involved in presynapse to nucleus signaling pathway IMP
IMP: Inferred from mutant phenotype
25652077 RGD
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IMP
IMP: Inferred from mutant phenotype
11590170 RGD
is active in extrinsic component of presynaptic endocytic zone membrane IDA
IDA: Inferred from direct assay
32075774 RGD
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
25652077 RGD
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
25652077 RGD
located in nucleus IMP
IMP: Inferred from mutant phenotype
11590170 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

C-terminal-binding protein 1

  • 50 kDa BFA-dependent ADP-ribosylation substrate

  • 50-kDa BFA-induced ADP-ribosylated substrate

  • C-terminal-binding protein 3

  • C-terminus binding protein 3/brefeldin A (BFA) adenosine diphosphate-ribosylated substrate

  • brefeldin A-ADP-riboslyated substrate

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-135046 MTOB sodium Inhibitor 97.02% Unkown
HY-RS03283 CTBP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19426 Ctbp1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25917 Ctbp1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ctbp1 NCBI NCBI:1487