Ahcy - adenosylhomocysteinase Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29443

Summary

Enables adenosylhomocysteinase activity; identical protein binding activity; and nucleotide binding activity. Involved in several processes, including S-adenosylhomocysteine catabolic process; chronic inflammatory response to antigenic stimulus; and circadian sleep/wake cycle. Located in cytosol; neuron projection; and nucleus. Used to study hyperhomocysteinemia and pyridoxine deficiency anemia. Human ortholog(s) of this gene implicated in hypermethioninemia with deficiency of S-adenosylhomocysteine hydrolase. Orthologous to human AHCY (adenosylhomocysteinase). [provided by Alliance of Genome Resources, Apr 2022]

Ahcy Products (1)

mRNA Protein Name
NM_017201.2 NP_058897.1 adenosylhomocysteinase

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Verweise Source
enables NAD binding IDA
IDA: Inferred from direct assay
2910349 RGD
enables adenosylhomocysteinase activity IDA
IDA: Inferred from direct assay
11741948 RGD
enables adenyl nucleotide binding IDA
IDA: Inferred from direct assay
9291120 RGD
enables identical protein binding IDA
IDA: Inferred from direct assay
2910349 RGD
Biological Process GO Annotation Evidence Verweise Source
involved in S-adenosylhomocysteine catabolic process IDA
IDA: Inferred from direct assay
11741948 RGD
involved in chronic inflammatory response to antigenic stimulus IMP
IMP: Inferred from mutant phenotype
11123369 RGD
involved in circadian sleep/wake cycle IDA
IDA: Inferred from direct assay
8330191 RGD
involved in response to hypoxia IEP
IEP: Inferred from expression pattern
10646513 RGD
involved in response to nutrient IDA
IDA: Inferred from direct assay
11575573 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

adenosylhomocysteinase

  • S-adenosyl-L-homocysteine hydrolase

  • S-adenosylhomocysteine hydrolase

  • adoHcyase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (7)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-10442 3-Deazaneplanocin A Inhibitor 99.97% Unkown
HY-12186 3-Deazaneplanocin A hydrochloride Inhibitor 99.98% Unkown
HY-112639 Aristeromycin Inhibitor 99.10% Unkown
HY-149048 Adenosylhomocysteinase / Unkown
HY-RS00476 AHCY Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16799 Ahcy Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23240 Ahcy Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ahcy NCBI NCBI:191