Aoc3 - amine oxidase, copper containing 3 Gene

Also Known as SSAO

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29473

Summary

Enables identical protein binding activity and primary amine oxidase activity. Involved in several processes, including eating behavior; leukocyte migration involved in inflammatory response; and positive regulation of glucose transmembrane transport. Located in extracellular space and intracellular membrane-bounded organelle. Used to study aortic aneurysm; obesity; type 2 diabetes mellitus; and uveitis. Biomarker of intracranial aneurysm. Orthologous to human AOC3 (amine oxidase copper containing 3). [provided by Alliance of Genome Resources, Apr 2022]

Aoc3 Products (1)

mRNA Protein Name
NM_031582.3 NP_113770.2 membrane primary amine oxidase

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
17393059 RGD
enables primary methylamine oxidase activity IDA
IDA: Inferred from direct assay
17393059 RGD
Biological Process GO Annotation Evidence References Source
involved in eating behavior IMP
IMP: Inferred from mutant phenotype
17977742 RGD
involved in leukocyte migration involved in inflammatory response IMP
IMP: Inferred from mutant phenotype
17993604 RGD
involved in positive regulation of D-glucose transmembrane transport IDA
IDA: Inferred from direct assay
15000445 RGD
involved in positive regulation of acute inflammatory response IMP
IMP: Inferred from mutant phenotype
17993604 RGD
involved in positive regulation of leukocyte migration IMP
IMP: Inferred from mutant phenotype
19635478 RGD
involved in regulation of blood pressure IMP
IMP: Inferred from mutant phenotype
17385063 RGD
involved in response to immobilization stress IMP
IMP: Inferred from mutant phenotype
11099833 RGD
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
10048142 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

membrane primary amine oxidase

  • VAP-1

  • VP97

  • copper amine oxidase

  • semicarbazide-sensitive amine oxidase

  • vascular adhesion protein 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00773 AOC3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17943 Aoc3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24414 Aoc3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Bioactive MoleculesInhibitory Antibodies (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P99323 Timolumab Inhibitor 98.56% Unkown
HY-P99526 Vapaliximab Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Aoc3 NCBI NCBI:8639