Nfya - nuclear transcription factor Y subunit alpha Gene

Also Known as CBF-A; CBF-B

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29508

Summary

Enables transcription coregulator binding activity. Predicted to be involved in positive regulation of transcription, DNA-templated and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within positive regulation of stem cell proliferation; positive regulation of transcription by RNA polymerase II; and regulation of stem cell population maintenance. Part of CCAAT-binding activity factor complex. Orthologous to human NFYA (nuclear transcription factor Y subunit alpha). [provided by Alliance of Genome Resources, Apr 2022]

Nfya Products (3)

mRNA Protein Name
NM_001413345.1 NP_001400274.1 nuclear transcription factor Y subunit alpha isoform 1
NM_001413346.1 NP_001400275.1 nuclear transcription factor Y subunit alpha isoform 3
NM_012865.3 NP_036997.1 nuclear transcription factor Y subunit alpha isoform 2

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
10393239 RGD
enables transcription coregulator binding IPI
IPI: Inferred from physical interaction
21164521 RGD
Cellular Component GO Annotation Evidence References Source
part of CCAAT-binding factor complex IDA
IDA: Inferred from direct assay
7878029 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

nuclear transcription factor Y subunit alpha

  • CAAT box DNA-binding protein subunit A

  • CCAAT-binding transcription factor subunit A

  • CCAAT-binding transcription factor subunit B

  • nuclear transcription factor Y subunit A

  • nuclear transcription factor-Y alpha

Nfya Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Nfya P18576 Sp1 Rattus norvegicus Q01714
Anti Bait CoIP
10393239
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-128020 ML114 Inhibitor / Unkown
HY-182392 NFYi5 / Unkown
HY-RS09271 NFYA Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20307 Nfya Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26815 Nfya Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28777 Nfyb Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nfya NCBI NCBI:4800