Zmynd8 - zinc finger, MYND-type containing 8 Gene

Also Known as spikar; Prkcbp1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 296374

Summary

Enables protein N-terminus binding activity. Involved in several processes, including positive regulation of dendritic spine development; positive regulation of filopodium assembly; and regulation of postsynapse organization. Located in cytoplasm; dendrite; and nucleus. Orthologous to human ZMYND8 (zinc finger MYND-type containing 8). [provided by Alliance of Genome Resources, Apr 2022]

Zmynd8 Products (1)

mRNA Protein Name
NM_001100838.1 NP_001094308.1 protein kinase C-binding protein 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
24117785 RGD
Biological Process GO Annotation Evidence References Source
involved in modulation of excitatory postsynaptic potential IMP
IMP: Inferred from mutant phenotype
24117785 RGD
involved in positive regulation of dendritic spine development IMP
IMP: Inferred from mutant phenotype
24117785 RGD
involved in positive regulation of dendritic spine maintenance IMP
IMP: Inferred from mutant phenotype
24117785 RGD
involved in positive regulation of filopodium assembly IMP
IMP: Inferred from mutant phenotype
24117785 RGD
involved in regulation of postsynaptic density protein 95 clustering IMP
IMP: Inferred from mutant phenotype
24117785 RGD
Cellular Component GO Annotation Evidence References Source
located in dendritic shaft IDA
IDA: Inferred from direct assay
24117785 RGD
located in dendritic spine IDA
IDA: Inferred from direct assay
24117785 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein kinase C-binding protein 1

  • spikar delta C

Zmynd8 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Zmynd8 A8C4G9 Dbn1 Rattus norvegicus Q07266
Pull Down
24117785
Intra
Zmynd8 A8C4G9 Dbn1 Rattus norvegicus Q07266
IF
24117785
Intra
Zmynd8 A8C4G9 Dbn1 Rattus norvegicus Q07266
Y2H
24117785
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-403538 iZMYND8-34 Inhibitor 98.89% Unkown
HY-RS16096 ZMYND8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20619 Zmynd8 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27127 Zmynd8 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Zmynd8 NCBI NCBI:23613