1. Gene
  2. SNX12 - sorting nexin 12 Gene

SNX12 - sorting nexin 12 Gene

Homo sapiens
Gene ID: 29934 | Gene type: protein coding

About SNX12

Cytogenetic location: Xq13.1 Genomic coordinates (GRCh38): X:71,059,247-71,073,426 (from NCBI)

This gene has 7 transcripts (splice variants), 215 orthologues and 15 paralogues. Ubiquitous expression in kidney (RPKM 19.5), thyroid (RPKM 17.8) and 25 other tissues.

Summary

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members. A similar protein in mouse may be involved in regulating the neurite outgrowth. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]

SNX12 Products(5)

mRNA Protein Name
NM_001256185.2 NP_001243114.1 sorting nexin-12 isoform 1
NM_001256186.2 NP_001243115.1 sorting nexin-12 isoform 2
NM_001256187.2 NP_001243116.1 sorting nexin-12 isoform 3
NM_001256188.2 NP_001243117.1 sorting nexin-12 isoform 4
NM_013346.4 NP_037478.2 sorting nexin-12 isoform 1

SNX12 Protein Structure

PX

PX: PX domain (28 - 148)

  • 0
  • 100
  • 162 a.a.
Protein Preferred Names Protein Names

sorting nexin-12

Orthologs Information

Species Symbol Source ID
Rattus norvegicus SNX12 RGD RGD:1565585
Felis catus SNX12 VGNC VGNC:65543
Bos taurus SNX12 VGNC VGNC:35093
Mus musculus SNX12 MGD MGI:1919331
Macaca mulatta SNX12 VGNC VGNC:77707