Casp14 - caspase 14 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 299587

Summary

Predicted to enable cysteine-type endopeptidase activity involved in execution phase of Apoptosis. Predicted to be involved in cornification; execution phase of apoptosis; and proteolysis. Located in keratin filament and nucleus. Human ortholog(s) of this gene implicated in autosomal recessive congenital ichthyosis. Orthologous to human CASP14 (Caspase 14). [provided by Alliance of Genome Resources, Apr 2022]

Casp14 Products (1)

mRNA Protein Name
NM_001191776.1 NP_001178705.1 caspase-14

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
located in keratin filament IDA
IDA: Inferred from direct assay
16142807 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

caspase-14

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-174458 MD-4251 Degrader / Unkown
HY-P11596 NOTA-Asp2-αvβ6L / Unkown
HY-RS01948 CASP14 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20533 Casp14 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27042 Casp14 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Casp14 NCBI NCBI:23581