1. Gene
  2. Pdcd1 - programmed cell death 1 Gene

Pdcd1 - programmed cell death 1 Gene

Rattus norvegicus
Gene ID: 301626 | Gene type: protein coding

About Pdcd1

Primary_assembly 9: 94,418,791-94,431,937 reverse strand.mRatBN7.2:CM026982.1

This gene has 1 transcript (splice variant), 106 orthologues and is associated with 59 phenotypes. Biased expression in Thymus (RPKM 22.3), Spleen (RPKM 5.7) and 3 other tissues.

Summary

Predicted to be involved in negative regulation of immune response and positive regulation of T cell apoptotic process. Predicted to act upstream of or within negative regulation of apoptotic process; negative regulation of tolerance induction; and positive regulation of apoptotic process. Located in plasma membrane. Biomarker of anti-basement membrane glomerulonephritis; periodontitis; and pre-eclampsia. Human ortholog(s) of this gene implicated in autoimmune disease (multiple); hepatitis B; hepatitis C; hepatocellular carcinoma; and lupus nephritis. Orthologous to human PDCD1 (programmed cell death 1). [provided by Alliance of Genome Resources, Apr 2022]

Pdcd1 Products(1)

mRNA Protein Name
NM_001106927.1 NP_001100397.1 programmed cell death protein 1 precursor

Pdcd1 Protein Structure

IgV_PD1

IgV_PD1: cd16088 (33 - 55)

IgV_PD1

IgV_PD1: cd16088 (33 - 144)

IgV_PD1

IgV_PD1: cd16088 (33 - 37)

IgV_PD1

IgV_PD1: cd16088 (40 - 43)

IgV_PD1

IgV_PD1: cd16088 (47 - 55)

IgV_PD1

IgV_PD1: cd16088 (56 - 62)

IgV_PD1

IgV_PD1: cd16088 (62 - 70)

IgV_PD1

IgV_PD1: cd16088 (63 - 72)

IgV_PD1

IgV_PD1: cd16088 (73 - 89)

IgV_PD1

IgV_PD1: cd16088 (73 - 82)

IgV_PD1

IgV_PD1: cd16088 (85 - 89)

IgV_PD1

IgV_PD1: cd16088 (93 - 127)

IgV_PD1

IgV_PD1: cd16088 (94 - 99)

IgV_PD1

IgV_PD1: cd16088 (104 - 111)

IgV_PD1

IgV_PD1: cd16088 (118 - 128)

IgV_PD1

IgV_PD1: cd16088 (128 - 131)

IgV_PD1

IgV_PD1: cd16088 (130 - 144)

IgV_PD1

IgV_PD1: cd16088 (131 - 144)

  • 0
  • 100
  • 200
  • 287 a.a.
Protein Preferred Names Protein Names

programmed cell death protein 1

programmed cell death protein 1-like

Recombinant Pdcd1 Proteins

Cat. No. Product Name Accession Purity
HY-P73347 PD-1 Protein, Rat (HEK293, His) D3ZIN8 (L25-Q167) ≥95%
HY-P73348 PD-1 Protein, Rat (HEK293, Fc) D3ZIN8 (M1-Q167) ≥95%

Orthologs Information

Species Symbol Source ID
Homo sapiens Pdcd1 NCBI NCBI:5133
Canis familiaris Pdcd1 NCBI NCBI:486213
Macaca fascicularis Pdcd1 NCBI NCBI:102123659
Mus musculus Pdcd1 NCBI NCBI:18566
Macaca mulatta Pdcd1 NCBI NCBI:100135775