Abl2 - ABL proto-oncogene 2, non-receptor tyrosine kinase Gene

Also Known as Arg; Abll

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 304883

Summary

Predicted to enable metal ion binding activity; phosphotyrosine residue binding activity; and protein tyrosine kinase activity. Predicted to be involved in several processes, including cellular response to retinoic acid; peptidyl-tyrosine phosphorylation; and synapse maturation. Predicted to act upstream of or within several processes, including nervous system development; regulation of signal transduction; and transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to be located in several cellular components, including dendritic spine; lamellipodium; and phagocytic cup. Predicted to be active in glutamatergic synapse. Orthologous to human ABL2 (ABL proto-oncogene 2, non-receptor tyrosine kinase). [provided by Alliance of Genome Resources, Apr 2022]

Abl2 Products (1)

mRNA Protein Name
NM_001395130.1 NP_001382059.1 tyrosine-protein kinase ABL2
Protein Preferred Names Protein Names

tyrosine-protein kinase ABL2

  • Abelson murine leukemia viral (v-abl) oncogene homolog 2

  • Abelson tyrosine-protein kinase 2

  • Abl1-related gene product

  • arg tyrosine kinase

  • c-abl oncogene 2, non-receptor tyrosine kinase

  • v-abl Abelson murine leukemia viral oncogene 2

  • v-abl Abelson muri

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-148794 Risvodetinib Inhibitor 99.21% Phase 2

Pre-clinical Phase

Bioactive Molecules (10)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-148061 DB1113 99.86% Unkown
HY-148063 DB0614 99.92% Unkown
HY-148066 DB0662 Degrader 99.66% Unkown
HY-178382 BRAFV600E/ABL2-IN-1 / Unkown
HY-181726 BRAFV600E/ABL2-IN-2 / Unkown
HY-182792 Embibatinib Inhibitor / Unkown
HY-184274 EGFR/c-SRC-IN-1 / Unkown
HY-RS00105 ABL2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18744 Abl2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25231 Abl2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Abl2 NCBI NCBI:27