Dsg2 - desmoglein 2 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 307562

Summary

Predicted to enable calcium ion binding activity and cell adhesion molecule binding activity. Involved in maternal process involved in female pregnancy and response to progesterone. Located in apical plasma membrane and lateral plasma membrane. Human ortholog(s) of this gene implicated in arrhythmogenic right ventricular dysplasia 10 and dilated cardiomyopathy 1BB. Orthologous to human DSG2 (desmoglein 2). [provided by Alliance of Genome Resources, Apr 2022]

Dsg2 Products (1)

mRNA Protein Name
XM_006254474.4 XP_006254536.1 desmoglein-2

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in maternal process involved in female pregnancy IEP
IEP: Inferred from expression pattern
15530549 RGD
involved in response to progesterone IEP
IEP: Inferred from expression pattern
15530549 RGD
Cellular Component GO Annotation Evidence References Source
located in apical plasma membrane IDA
IDA: Inferred from direct assay
10937559 RGD
located in intercalated disc IDA
IDA: Inferred from direct assay
25332002 RGD
located in lateral plasma membrane IDA
IDA: Inferred from direct assay
15530549 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

desmoglein-2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04022 DSG2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17686 Dsg2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24147 Dsg2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dsg2 NCBI NCBI:1829