Setd1a - SET domain containing 1A, histone lysine methyltransferase Gene
Also Known as RGD1311624
Species: Rattus norvegicus
Summary
Predicted to enable beta-catenin binding activity and Histone Methyltransferase activity (H3-K4 specific). Predicted to be involved in several processes, including histone H3-K4 methylation; regulation of erythrocyte differentiation; and regulation of hematopoietic stem cell differentiation. Predicted to act upstream of or within histone H3-K4 methylation; positive regulation of cell population proliferation; and stem cell population maintenance. Predicted to be located in euchromatin and nuclear speck. Predicted to be part of Set1C/COMPASS complex. Orthologous to human SETD1A (SET domain containing 1A, histone lysine methyltransferase). [provided by Alliance of Genome Resources, Apr 2022]
Setd1a Products (7)
| mRNA | Protein | Name |
|---|---|---|
| XM_039101225.1 | XP_038957153.1 | histone-lysine N-methyltransferase SETD1A isoform X1 |
| XM_039101222.1 | XP_038957150.1 | histone-lysine N-methyltransferase SETD1A isoform X1 |
| XM_039101223.1 | XP_038957151.1 | histone-lysine N-methyltransferase SETD1A isoform X1 |
| XM_039101221.1 | XP_038957149.1 | histone-lysine N-methyltransferase SETD1A isoform X1 |
| XM_039101227.1 | XP_038957155.1 | histone-lysine N-methyltransferase SETD1A isoform X2 |
| XM_039101224.1 | XP_038957152.1 | histone-lysine N-methyltransferase SETD1A isoform X1 |
| XM_039101226.1 | XP_038957154.1 | histone-lysine N-methyltransferase SETD1A isoform X1 |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
histone-lysine N-methyltransferase SETD1A |
|