Kdm3a - lysine demethylase 3A Gene

Also Known as Jmjd1; Jmjd1a

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 312440

Summary

Predicted to enable several functions, including Androgen Receptor binding activity; chromatin DNA binding activity; and iron ion binding activity. Involved in male gonad development; positive regulation of gene expression; and response to hypoxia. Predicted to be located in cytoplasm and nucleoplasm. Predicted to be part of histone deacetylase complex. Predicted to be active in chromatin. Human ortholog(s) of this gene implicated in cervical Cancer and colon Cancer. Orthologous to human KDM3A (lysine demethylase 3A). [provided by Alliance of Genome Resources, Apr 2022]

Kdm3a Products (2)

mRNA Protein Name
NM_001389240.1 NP_001376169.1 lysine-specific demethylase 3A isoform 1
NM_175764.3 NP_786940.2 lysine-specific demethylase 3A isoform 2

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in male gonad development IEP
IEP: Inferred from expression pattern
1793593 RGD
involved in positive regulation of gene expression IMP
IMP: Inferred from mutant phenotype
18538129 RGD
involved in response to hypoxia IEP
IEP: Inferred from expression pattern
18538129 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

lysine-specific demethylase 3A

  • [histone H3]-dimethyl-L-lysine(9) demethylase 3A

  • jmjC domain-containing histone demethylation protein 2A

  • jumonji domain containing 1A

  • jumonji domain-containing protein 1A

  • lysine (K)-specific demethylase 3A

  • probable zinc finger protein

  • testis-specifi

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-12304 IOX1 Inhibitor 99.89% Unkown
HY-168593 PROTAC KDM3 degrader-1 99.07% Unkown
HY-RS07211 KDM3A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-183618 DW-229 Degrader / Unkown
HY-RS17111 Kdm3a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23556 Kdm3a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kdm3a NCBI NCBI:55818