2. Gene
  3. KDM3A - lysine demethylase 3A Gene

KDM3A - lysine demethylase 3A Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as TSGA; JMJD1; JHDM2A; JHMD2A; JMJD1A

Gene ID: 55818 | Gene type: protein coding

About KDM3A

Cytogenetic location: 2p11.2 Genomic coordinates (GRCh38): 2:86,437,044-86,492,716 (from NCBI)

This gene has 15 transcripts (splice variants), 128 orthologues and 3 paralogues. Ubiquitous expression in testis (RPKM 32.2), bone marrow (RPKM 27.1) and 25 other tissues.

Summary

This gene encodes a zinc finger protein that contains a jumonji domain and may play a role in hormone-dependent transcriptional activation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]

KDM3A Products(2)

mRNA Protein Name
NM_001146688.2 NP_001140160.1 lysine-specific demethylase 3A
NM_018433.6 NP_060903.2 lysine-specific demethylase 3A

KDM3A Protein Structure

JmjC

JmjC: JmjC domain, hydroxylase (1155 - 1264)

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  • 1321 a.a.
Protein Preferred Names Protein Names

lysine-specific demethylase 3A

[histone H3]-dimethyl-L-lysine(9) demethylase 3A

Related Diseases

Diseases Alias
Male Infertility

Infertility, Male

Infertility Male

Male Sterility

Absolute Infertility
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-12304 IOX1 Inhibitor 99.72% Unkown
HY-RS07211 KDM3A Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris KDM3A VGNC VGNC:42322
Bos taurus KDM3A VGNC VGNC:30525
Rattus norvegicus KDM3A RGD RGD:708351
Mus musculus KDM3A MGD MGI:98847
Felis catus KDM3A VGNC VGNC:63070
Macaca mulatta KDM3A VGNC VGNC:73871