Stk11 - serine/threonine kinase 11 Gene

Also Known as Lkb1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 314621

Summary

Enables protein serine/threonine kinase activity. Involved in several processes, including positive regulation of gluconeogenesis; response to glucagon; and response to thyroid hormone. Located in nucleus. Part of protein-containing complex. Colocalizes with Z disc. Biomarker of hyperthyroidism and obesity. Human ortholog(s) of this gene implicated in Peutz-Jeghers syndrome; familial melanoma; female reproductive organ Cancer (multiple); and pancreatic Cancer. Orthologous to human STK11 (serine/threonine kinase 11). [provided by Alliance of Genome Resources, Apr 2022]

Stk11 Products (1)

mRNA Protein Name
NM_001108069.2 NP_001101539.1 serine/threonine-protein kinase STK11
Protein Preferred Names Protein Names

serine/threonine-protein kinase STK11

  • liver kinase B1 homolog

  • serine/threonine-protein kinase 11

  • serine/threonine-protein kinase LKB1

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-153358 TNG260 Inhibitor 99.33% Phase 2

Pre-clinical Phase

Bioactive Molecules (7)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P5435 LKBtide Substrate 95.59% Unkown
HY-153358A (S)-TNG260 98.39% Unkown
HY-RS13921 STK11 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-N6904 Crocetin monomethyl ester Inhibitor 98.44% Unkown
HY-RS13922 STK11IP Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17308 Stk11 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23763 Stk11 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Stk11 NCBI NCBI:6794