Tph2 - tryptophan hydroxylase 2 Gene

Also Known as Ntph

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 317675

Summary

Predicted to enable tryptophan 5-monooxygenase activity. Involved in several processes, including cellular response to lithium ion; response to activity; and response to estrogen. Predicted to be active in neuron projection. Human ortholog(s) of this gene implicated in attention deficit hyperactivity disorder; autistic disorder; major depressive disorder; and panic disorder. Orthologous to human TPH2 (Tryptophan Hydroxylase 2). [provided by Alliance of Genome Resources, Apr 2022]

Tph2 Products (1)

mRNA Protein Name
NM_173839.3 NP_776211.1 tryptophan 5-hydroxylase 2
Protein Preferred Names Protein Names

tryptophan 5-hydroxylase 2

  • neuronal tryptophan hydroxylase

  • tryptophan 5-monooxygenase 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (8)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-W019599 4-Chloro-L-phenylalanine Inhibitor 98.19% Unkown
HY-120083 Rodatristat Inhibitor 98.41% Unkown
HY-157014 TPT-004 Inhibitor 99.90% Unkown
HY-181575 TPH2 agonist-1 Inhibitor / Unkown
HY-RS14331 TDO2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14933 TPH2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17651 Tph2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24111 Tph2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tph2 NCBI NCBI:121278