Itgb8 - integrin beta 8 Gene

Also Known as 4832412O06Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 320910

Summary

Predicted to enable extracellular matrix protein binding activity and Integrin binding activity. Involved in regulation of transforming growth factor beta activation. Acts upstream of or within several processes, including Langerhans cell differentiation; ganglioside metabolic process; and hard palate development. Part of Integrin alphav-beta8 complex. Is expressed in several structures, including axial skeleton; hindlimb phalanx; nervous system; reproductive system; and sensory organ. Orthologous to human ITGB8 (Integrin subunit beta 8). [provided by Alliance of Genome Resources, Apr 2022]

Itgb8 Products (1)

mRNA Protein Name
NM_177290.4 NP_796264.2 integrin beta-8 precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within Langerhans cell differentiation IGI
IGI: Inferred from genetic interaction
19118215 MGI
acts upstream of or within ganglioside metabolic process IMP
IMP: Inferred from mutant phenotype
16251442 MGI
acts upstream of or within hard palate development IGI
IGI: Inferred from genetic interaction
19118215 MGI
acts upstream of or within immune response IGI
IGI: Inferred from genetic interaction
19118215 MGI
acts upstream of or within response to virus IGI
IGI: Inferred from genetic interaction
30952606 MGI
acts upstream of or within transforming growth factor beta receptor signaling pathway IGI
IGI: Inferred from genetic interaction
30952606 MGI
Cellular Component GO Annotation Evidence References Source
part of integrin alphav-beta8 complex IDA
IDA: Inferred from direct assay
22278742 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

integrin beta-8

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06972 ITGB8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17983 Itgb8 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24454 Itgb8 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Itgb8 NCBI NCBI:3696