2. Gene
  3. HSPA1B - heat shock protein family A (Hsp70) member 1B Gene

HSPA1B - heat shock protein family A (Hsp70) member 1B Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as HSP72; HSPA1; HSX70; HSP70-1; HSP70-2; HSP70.1; HSP70.2; HSP70-1B

Gene ID: 3304 | Gene type: protein coding

About HSPA1B

Cytogenetic location: 6p21.33 Genomic coordinates (GRCh38): 6:31,827,738-31,830,254 (from NCBI)

This gene has 1 transcript (splice variant), 1 gene allele, 142 orthologues and 13 paralogues.

Summary

This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins. [provided by RefSeq, Jul 2008]

HSPA1B Products(1)

mRNA Protein Name
NM_005346.6 NP_005337.2 heat shock 70 kDa protein 1B

HSPA1B Protein Structure

HSP70

HSP70: Hsp70 protein (6 - 612)

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  • 641 a.a.
Protein Preferred Names Protein Names

heat shock 70 kDa protein 1B

HSP70-1/HSP70-2

Recombinant HSPA1B Proteins

Cat. No. Product Name Accession Purity
HY-P73105 HSP70/HSPA1B Protein, Human (SF9, His) P0DMV9 (A2-D641) ≥95%
HY-P74877 HSP70/HSPA1A Protein, Human (HEK293, His) P0DMV8 (A2-D641) ≥95%
HY-P701004 HSP70/HSPA1A Protein, Human (E110D, His) P0DMV8-1 (A2-D641, E110D) ≥95%

Related Diseases

Diseases Alias
Systemic Lupus Erythematosus

Lupus Nephritis

SLE

Disseminated Lupus Erythematosus

Systemic Lupus Erythematosus, Susceptibility To

Lupus Erythematosus, Systemic

Lupus Nephritis, Susceptibility To

Libman-Sacks Disease

Systemic Lupus Erythematosus Susceptibility To

Sle - Lupus Erythematosus, Systemic

Le Syndrome

Lupus

Lupus Erythematosus Systemic

Lupus Erythematosus, Systemic, Susceptibility To

Lupus Vulgaris

Lupus Erythematosus, Discoid

Lupus Erythematosus

Systemic Lupus Erythematosus Nos

Sle - [Systemic Lupus Erythematosus]
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06425 HSPA1B Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus HSPA1B RGD RGD:2840
Mus musculus HSPA1B MGD MGI:99517