IGHG1 - immunoglobulin heavy constant gamma 1 (G1m marker) Gene

Homo sapiens

Gene ID: 3500 | Gene type: other

About IGHG1

Cytogenetic location: 14q32.33 Genomic coordinates (GRCh38): 14:105,741,473-105,743,070 (from NCBI)

This gene has 3 transcripts (splice variants), 1 gene allele, 119 orthologues, 82 paralogues and is associated with 2 phenotypes.

Summary

Predicted to enable antigen binding activity and immunoglobulin receptor binding activity. Predicted to be involved in several processes, including activation of immune response; defense response to other organism; and phagocytosis. Predicted to act upstream of or within several processes, including immunoglobulin mediated immune response; positive regulation of hypersensitivity; and positive regulation of phagocytosis. Located in extracellular space. [provided by Alliance of Genome Resources, Apr 2022]

IGHG1 Protein Structure

C1-set

0
100
200
300
330 a.a.

Recombinant IGHG1 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P72379	IgG1 Protein, Human (Biotinylated, HEK293, Avi)	P01857 (D104-K330, D239E, L241M)	≥95%
HY-P73143	IgG1 Protein, Human (C103S, HEK293)	P01857 (E99-K330, C103S)	≥95%
HY-P73902	IgG1 Protein, Human (CHO, C103S)	P01857 (E99-K330, C103S)	≥95%
HY-P73903	IgG1 Protein, Human (CHO)	P01857-1 (E99-K330, C103S)	≥95%
HY-P77526	IgG1 Protein, Human (Biotinylated, C103S, HEK293)	P01857-1 (E99-K330, C103S)	≥95%

Related Diseases

Diseases

Alias

Leukemia, Chronic Lymphocytic

Chronic Lymphocytic Leukemia	B-Cell Chronic Lymphocytic Leukemia
CLL	B-Cell Chronic Lymphoid Leukemia
Chronic Lymphatic Leukemia	Chronic Lymphocytic Leukaemia
Lymphoplasmacytic Leukemia	Small Lymphocytic Lymphoma
Leukemia, Chronic Lymphatic	B-Cell Chronic Lymphocytic Leukaemia
Chronic Lymphatic Leukaemia	Lymphoplasmacytic Leukaemia
B Cell Chronic Lymphocytic Leukemia	Chronic B-Cell Lymphocytic Leukemia
Leukemia, Lymphocytic, Chronic	B-Cll
Chronic Lymphoid Leukemia	Leukemia Lymphocytic Chronic
Lymphoma Small Lymphocytic	Leukemia, Lymphocytic, Chronic, B-Cell

Amyloidosis

Amyloid Disease	Amyloid
Amyloid Degeneration	Amyloidosis Nos
Amyloid Deposition	Amyloid Infiltration
Idiopathic Amyloidosis	Hyaloid Degeneration
Lardaceous Degeneration

Plasma Cell Leukemia

Plasma Cell Leukaemia	Leukemia, Plasma Cell
Plasmacytic Leukaemia	Plasmacytic Leukemia
Pcl	Plasma Cell Leukaemia, Nos
Leukemic Plasma Cell	Plasma Cell Leukaemia Without Mention Of Remission

Systemic Lupus Erythematosus

Lupus Nephritis	SLE
Disseminated Lupus Erythematosus	Systemic Lupus Erythematosus, Susceptibility To
Lupus Erythematosus, Systemic	Lupus Nephritis, Susceptibility To
Libman-Sacks Disease	Systemic Lupus Erythematosus Susceptibility To
Sle - Lupus Erythematosus, Systemic	Le Syndrome
Lupus	Lupus Erythematosus Systemic
Lupus Erythematosus, Systemic, Susceptibility To	Lupus Vulgaris
Lupus Erythematosus, Discoid	Lupus Erythematosus
Systemic Lupus Erythematosus Nos	Sle - [Systemic Lupus Erythematosus]

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Clinical Phase

Inhibitory Antibodies (2)

Cat. No.	Product Name	Effect	Purity	Phase
HY-P99830	Conbercept		/	Phase 4
HY-P99844	Davoceticept		/	Phase 1

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	IGHG1	RGD	RGD:1359539
Mus musculus	IGHG1	NCBI

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