Traf7 - TNF receptor associated factor 7 Gene

Also Known as RGD1559653

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 360491

Summary

Predicted to enable ubiquitin-protein transferase activity. Predicted to be involved in several processes, including Notch signaling pathway; regulation of signal transduction; and ribosomal large subunit assembly. Predicted to act upstream of or within several processes, including cellular response to interleukin-6; positive regulation of MAPK cascade; and positive regulation of protein sumoylation. Predicted to be located in several cellular components, including cytosol; nucleus; and perinuclear region of cytoplasm. Predicted to be part of ubiquitin Ligase complex. Predicted to be active in nucleolus. Orthologous to human TRAF7 (TNF Receptor associated factor 7). [provided by Alliance of Genome Resources, Apr 2022]

Traf7 Products (1)

mRNA Protein Name
NM_001127548.1 NP_001121020.1 E3 ubiquitin-protein ligase TRAF7

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in positive regulation of neuron apoptotic process IMP
IMP: Inferred from mutant phenotype
30100091 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase TRAF7

  • TNF receptor-associated factor 7, E3 ubiquitin protein ligase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14976 TRAF7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20502 Traf7 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27010 Traf7 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Traf7 NCBI NCBI:84231