DOCK2 - Dock2 dedicator of cytokinesis 2 Gene
Also Known as AABR07029272.1
Species: Rattus norvegicus
Gene Type: protein coding
Gene ID: 360509
Summary
Predicted to enable GTPase activator activity; T cell receptor binding activity; and guanyl-nucleotide exchange factor activity. Predicted to be involved in macropinocytosis; myeloid dendritic cell activation involved in immune response; and positive regulation of phagocytosis. Predicted to act upstream of or within several processes, including T cell activation; immunological synapse formation; and membrane raft polarization. Human ortholog(s) of this gene implicated in immunodeficiency 40. Orthologous to human DOCK2 (dedicator of cytokinesis 2). [provided by Alliance of Genome Resources, Apr 2022]
DOCK2 Products (5)
| mRNA | Protein | Name |
|---|---|---|
| XM_039087139.1 | XP_038943067.1 | dedicator of cytokinesis protein 2 isoform X1 |
| XM_039087140.1 | XP_038943068.1 | dedicator of cytokinesis protein 2 isoform X2 |
| XM_039087141.1 | XP_038943069.1 | dedicator of cytokinesis protein 2 isoform X3 |
| XM_039087143.1 | XP_038943071.1 | dedicator of cytokinesis protein 2 isoform X5 |
| XM_039087142.1 | XP_038943070.1 | dedicator of cytokinesis protein 2 isoform X4 |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
dedicator of cytokinesis protein 2 |
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
Bioactive Molecules
(2)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-111355 | Cholesterol sulfate | Inhibitor | / | Unkown |
| HY-153128 | DOCK2-IN-1 | Inhibitor | 99.37% | Unkown |
Compound Screening Libraries
Virtual Screening
Customize Your Library
Drug Screening Service