Kif14 - kinesin family member 14 Gene

Predicted to enable several functions, including ATP binding activity; ATP hydrolysis activity; and PDZ domain binding activity. Predicted to be involved in several processes, including SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; brain development; and regulation of cell cycle process. Predicted to act upstream of or within several processes, including negative regulation of Integrin activation; regulation of Rap protein signal transduction; and substrate adhesion-dependent cell spreading. Predicted to be located in Flemming body; cytosol; and spindle midzone. Predicted to be part of Kinesin complex. Predicted to be active in microtubule. Predicted to colocalize with plasma membrane. Human ortholog(s) of this gene implicated in Meckel syndrome and primary autosomal recessive microcephaly. Orthologous to human KIF14 (Kinesin family member 14). [provided by Alliance of Genome Resources, Apr 2022]