Pnpt1 - polyribonucleotide nucleotidyltransferase 1 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 360992

Summary

Enables polyribonucleotide nucleotidyltransferase activity. Involved in several processes, including liver regeneration; response to cAMP; and response to growth hormone. Located in endoplasmic reticulum membrane; nucleus; and polysomal ribosome. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 70 and combined Oxidative Phosphorylation deficiency 13. Orthologous to human PNPT1 (polyribonucleotide nucleotidyltransferase 1). [provided by Alliance of Genome Resources, Apr 2022]

Pnpt1 Products (1)

mRNA Protein Name
NM_001142371.1 NP_001135843.1 polyribonucleotide nucleotidyltransferase 1, mitochondrial

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables polyribonucleotide nucleotidyltransferase activity IDA
IDA: Inferred from direct assay
7295810 RGD
Biological Process GO Annotation Evidence References Source
involved in liver regeneration IEP
IEP: Inferred from expression pattern
191106 RGD
involved in positive regulation of mRNA catabolic process IDA
IDA: Inferred from direct assay
737213 RGD
involved in response to cAMP IEP
IEP: Inferred from expression pattern
189502 RGD
involved in response to growth hormone IEP
IEP: Inferred from expression pattern
7470604 RGD
Cellular Component GO Annotation Evidence References Source
located in endoplasmic reticulum membrane IDA
IDA: Inferred from direct assay
191106 RGD
located in ribosome IDA
IDA: Inferred from direct assay
191106 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

polyribonucleotide nucleotidyltransferase 1, mitochondrial

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10801 PNPT1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21028 Pnpt1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27545 Pnpt1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Bioactive MoleculesInhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P991956 ABB071 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pnpt1 NCBI NCBI:87178