IMPA2 - inositol monophosphatase 2 Gene

Homo sapiens

Gene ID: 3613 | Gene type: protein coding

About IMPA2

Cytogenetic location: 18p11.21 Genomic coordinates (GRCh38): 18:11,981,507-12,030,877 (from NCBI)

This gene has 12 transcripts (splice variants), 158 orthologues and 4 paralogues. Broad expression in kidney (RPKM 73.3), skin (RPKM 38.8) and 18 other tissues.

Summary

This locus encodes an inositol monophosphatase. The encoded protein catalyzes the dephosphoylration of inositol monophosphate and plays an important role in phosphatidylinositol signaling. This locus may be associated with susceptibility to bipolar disorder. [provided by RefSeq, Jan 2011]

IMPA2 Products(1)

mRNA	Protein	Name
NM_014214.3	NP_055029.1	inositol monophosphatase 2

IMPA2 Protein Structure

Inositol_P

0
100
200
288 a.a.

Protein Preferred Names

Protein Names

inositol monophosphatase 2

IMP 2

Recombinant IMPA2 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P70197	IMPA2 Protein, Human (His)	O14732 (M1-K288)	≥95%

Related Diseases

Diseases

Alias

Bipolar Disorder

Bipolar Depression	Manic Disorder
Depression, Bipolar	Bipolar Disorder Manic Phase
Depressive-Manic Psych.	Manic Bipolar Affective Disorder
Manic Bipolar I Disorder	Manic Depression
Manic Depressive Disorder	Mixed Bipolar Disorder
Bipolar Affective Disorder	Bipolar Affective Psychosis
Bipolar Spectrum Disorder	Manic Depressive Illness
Depression Bipolar	Bipolar Disorder, Mixed
Major Affective Disorder	Major Affective Disorder 1
Major Affective Disorder 2

Febrile Seizures

Febrile Seizure	Febrile Convulsions
Seizures Febrile

Mood Disorder

Mood Disorders

Episodic Mood Disorder

Ring Dermoid Of Cornea

RDC	Ring Dermoid Syndrome
Bilateral, Annular Limbal Dermoids With Corneal And Conjunctival Extension	Dermoid Of Cornea, Ring

Schizophrenia

SCZD	Schizophrenia With Or Without An Affective Disorder
Schizophrenia 12	Schizophrenia, Susceptibility To
Schizophrenia-1	Dementia Praecox
Schizophrenia 1

Familial Febrile Seizures

Familial Febrile Convulsions	Feb
Febrile Seizures, Familial

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS06796	IMPA2 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	IMPA2	RGD	RGD:628692
Canis familiaris	IMPA2	VGNC	VGNC:49913
Mus musculus	IMPA2	MGD	MGI:2149728
Bos taurus	IMPA2	VGNC	VGNC:30185
Others	IMPA2	NCBI

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