Syvn1 - synoviolin 1 Gene

Predicted to enable several functions, including chaperone binding activity; enzyme binding activity; and unfolded protein binding activity. Predicted to be involved in several processes, including protein K48-linked ubiquitination; protein stabilization; and proteolysis involved in cellular protein catabolic process. Predicted to act upstream of or within in utero embryonic development; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway; and ubiquitin-dependent ERAD pathway. Predicted to be located in endoplasmic reticulum quality control compartment; nucleoplasm; and smooth endoplasmic reticulum. Predicted to be part of Derlin-1 retrotranslocation complex and Hrd1p ubiquitin Ligase ERAD-L complex. Predicted to be active in cytoplasm. Orthologous to human SYVN1 (synoviolin 1). [provided by Alliance of Genome Resources, Apr 2022]