Itga8 - integrin subunit alpha 8 Gene

Also Known as RGD1564327

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 364786

Summary

Involved in brain development. Located in dendritic spine membrane; perikaryon; and postsynaptic density. Biomarker of mesangial proliferative glomerulonephritis. Human ortholog(s) of this gene implicated in end stage renal disease; ovarian cancer; renal agenesis; and schizophrenia. Orthologous to human ITGA8 (Integrin subunit alpha 8). [provided by Alliance of Genome Resources, Apr 2022]

Itga8 Products (1)

mRNA Protein Name
NM_001173972.1 NP_001167443.1 integrin alpha-8

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
located in dendritic spine membrane IDA
IDA: Inferred from direct assay
8797161 RGD
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
8797161 RGD
located in perikaryon IDA
IDA: Inferred from direct assay
8797161 RGD
is active in postsynaptic density membrane IDA
IDA: Inferred from direct assay
8797161 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

integrin alpha-8

  • integrin, alpha 8

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06955 ITGA8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19450 Itga8 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25942 Itga8 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Itga8 NCBI NCBI:8516