2. Gene
  3. Kif14 - kinesin family member 14 Gene

Kif14 - kinesin family member 14 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as D1Ertd367e; E130203M01

Gene ID: 381293 | Gene type: protein coding

About Kif14

Chromosome 1: 136,394,081-136,459,249 forward strand.GRCm39:CM000994.3

This gene has 8 transcripts (splice variants), 199 orthologues, 43 paralogues and is associated with 32 phenotypes. Biased expression in liver E14 (RPKM 3.3), liver E14.5 (RPKM 2.8) and 14 other tissues.

Summary

Enables ATP binding activity; microtubule binding activity; and plus-end-directed microtubule motor activity. Involved in several processes, including brain development; negative regulation of neuron apoptotic process; and regulation of myelination. Predicted to be located in Flemming body; cytosol; and spindle midzone. Predicted to be part of Kinesin complex. Predicted to be active in microtubule. Predicted to colocalize with plasma membrane. Is expressed in retina. Human ortholog(s) of this gene implicated in Meckel syndrome and primary autosomal recessive microcephaly. Orthologous to human KIF14 (Kinesin family member 14). [provided by Alliance of Genome Resources, Apr 2022]

Kif14 Products(1)

mRNA Protein Name
NM_001287179.2 NP_001274108.1 kinesin-like protein KIF14

Kif14 Protein Structure

KISc_KIF1A_KIF1B

KISc_KIF1A_KIF1B: cd01365 (391 - 742)

Kinesin_assoc

Kinesin_assoc: cl24686 (739 - 858)

FHA_KIF14

FHA_KIF14: cd22707 (828 - 935)

SMC_prok_B

SMC_prok_B: cl37069 (936 - 1108)

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  • 1674 a.a.
Protein Preferred Names Protein Names

kinesin-like protein KIF14

N-3 kinesin

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07261 KIF14 Human Pre-designed siRNA Set A / Unkown
HY-RS07262 Kif14 Mouse Pre-designed siRNA Set A / Unkown
HY-RS07263 Kif14 Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kif14 NCBI NCBI:9928