KIFC1 - kinesin family member C1 Gene

Also Known as HSET; KNSL2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 3833

About KIFC1

Cytogenetic location: 6p21.32 Genomic coordinates (GRCh38): 6:33,391,461-33,409,896 (from NCBI)

This gene has 4 transcripts (splice variants), 1 gene allele, 141 orthologues and 41 paralogues. Broad expression in bone marrow (RPKM 10.5), lymph node (RPKM 9.0) and 15 other tissues.

Summary

Predicted to enable microtubule binding activity and minus-end-directed microtubule motor activity. Involved in mitotic metaphase plate congression and mitotic spindle assembly. Located in membrane. [provided by Alliance of Genome Resources, Apr 2022]

KIFC1 Products (1)

mRNA Protein Name
NM_002263.4 NP_002254.2 kinesin-like protein KIFC1

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in mitotic metaphase chromosome alignment IMP
IMP: Inferred from mutant phenotype
15843429 GOA
involved in mitotic spindle assembly IMP
IMP: Inferred from mutant phenotype
15843429 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

KIFC1 Protein Structure

Kinesin

Kinesin: Kinesin motor domain (368 - 662)

  • 0
  • 200
  • 400
  • 600
  • 673 a.a.
Protein Preferred Names Protein Names

kinesin-like protein KIFC1

  • kinesin-like 2

KIFC1 Antibodies

Cat. No. Product Name Application Reactivity
HY-P83397 KIFC1 Antibody (YA3142) WB, IHC-F, IHC-P, ICC/IF, FC, IP Human
HY-P83397A KIFC1 Antibody (YA3142)(PBS only) WB, IHC-F, IHC-P, ICC/IF, FC, IP Human

Related Diseases

Diseases Alias
Peritoneal Serous Adenocarcinoma

  • Primary Peritoneal Serous Adenocarcinoma
Invasive Bladder Transitional Cell Carcinoma

  • Invasive Bladder Urothelial Carcinoma

  • Infiltrating Bladder Urothelial Carcinoma
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (7)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-12241 AZ82 Inhibitor 99.86% Unkown
HY-118961 SR31527 chloride Inhibitor 97.35% Unkown
HY-RS07298 KIFC1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-180304 CCT369834 Inhibitor / Unkown
HY-N11128 Solidagonic acid Inhibitor / Unkown
HY-RS19017 Kifc1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25506 Kifc1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus KIFC1 VGNC VGNC:102446
Canis familiaris KIFC1 VGNC VGNC:42414
Macaca mulatta KIFC1 VGNC VGNC:74031
Mus musculus KIFC1 MGD MGI:2137414
Bos taurus KIFC1 VGNC VGNC:30611
Rattus norvegicus KIFC1 RGD RGD:1359118
Others KIFC1 NCBI