GRXCR1 - glutaredoxin and cysteine rich domain containing 1 Gene

Also Known as DFNB25; PPP1R88

Species: Homo sapiens (human)

Gene Type: protein coding
Gene ID: 389207

Summary

This gene is one of 60 loci associated with autosomal-recessive nonsyndromic hearing impairment. This gene encodes a protein which contains GRX-like domains; these domains play a role in the S-glutathionylation of proteins and may be involved in actin organization in hair cells. [provided by RefSeq, Sep 2010]

GRXCR1 Products (1)

mRNA Protein Name
NM_001080476.3 NP_001073945.1 glutaredoxin domain-containing cysteine-rich protein 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

glutaredoxin domain-containing cysteine-rich protein 1

  • glutaredoxin, cysteine rich 1

  • protein phosphatase 1, regulatory subunit 88

GRXCR1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
GRXCR1 A8MXD5 CAP2 Homo sapiens P40123
Y2H Prey Pooling
32296183
Intra
GRXCR1 A8MXD5 CAP2 Homo sapiens P40123
Validated Y2H
32296183
Intra
GRXCR1 A8MXD5 CAP2 Homo sapiens P40123
Y2H Array
32296183
Intra
GRXCR1 A8MXD5 PRDM6 Homo sapiens Q9NQX0
Y2H Prey Pooling
32296183
Intra
GRXCR1 A8MXD5 PRDM6 Homo sapiens Q9NQX0
Validated Y2H
32296183
Intra
GRXCR1 A8MXD5 PRDM6 Homo sapiens Q9NQX0
Y2H Array
32296183
Intra
GRXCR1 A8MXD5 TEX11 Homo sapiens Q8IYF3-3
Y2H Prey Pooling
32296183
Intra
GRXCR1 A8MXD5 TEX11 Homo sapiens Q8IYF3-3
Y2H Array
32296183
Intra
GRXCR1 A8MXD5 TEX11 Homo sapiens Q8IYF3-3
Validated Y2H
32296183
Intra
GRXCR1 A8MXD5 ALAS1 Homo sapiens P13196
Validated Y2H
32296183
Intra
GRXCR1 A8MXD5 ALAS1 Homo sapiens P13196
Y2H Array
32296183
Intra
GRXCR1 A8MXD5 ALAS1 Homo sapiens P13196
Y2H Prey Pooling
32296183
Intra
GRXCR1 A8MXD5 INCA1 Homo sapiens Q0VD86
Y2H Prey Pooling
32296183
Intra
GRXCR1 A8MXD5 INCA1 Homo sapiens Q0VD86
Validated Y2H
32296183
Intra
GRXCR1 A8MXD5 INCA1 Homo sapiens Q0VD86
Y2H Array
32296183
Intra
GRXCR1 A8MXD5 SDCBP Homo sapiens O00560
Validated Y2H
32296183
Intra
GRXCR1 A8MXD5 PICK1 Homo sapiens Q9NRD5
Y2H Prey Pooling
32296183
Intra
GRXCR1 A8MXD5 PICK1 Homo sapiens Q9NRD5
Validated Y2H
32296183
Intra
GRXCR1 A8MXD5 PICK1 Homo sapiens Q9NRD5
Y2H Array
32296183
Intra
GRXCR1 A8MXD5 SNX32 Homo sapiens Q86XE0
Y2H Prey Pooling
32296183
Intra
GRXCR1 A8MXD5 SNX32 Homo sapiens Q86XE0
Validated Y2H
32296183
Intra
GRXCR1 A8MXD5 SNX32 Homo sapiens Q86XE0
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction