LALBA - lactalbumin alpha Gene

Also Known as LYZG; HAMLET

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 3906

About LALBA

Cytogenetic location: 12q13.11 Genomic coordinates (GRCh38): 12:48,567,684-48,571,845 (from NCBI)

This gene has 2 transcripts (splice variants), 109 orthologues and 8 paralogues. Low expression observed in reference dataset.

Summary

This gene encodes alpha-lactalbumin, a principal protein of milk. Alpha-lactalbumin forms the regulatory subunit of the lactose synthase (LS) heterodimer and beta 1,4-galactosyltransferase (beta4Gal-T1) forms the catalytic component. Together, these proteins enable LS to produce lactose by transfering galactose moieties to glucose. As a monomer, alpha-lactalbumin strongly binds calcium and zinc ions and may possess bactericidal or antitumor activity. A folding variant of alpha-lactalbumin, called HAMLET, likely induces Apoptosis in tumor and immature cells. [provided by RefSeq, Jul 2008]

LALBA Products (2)

mRNA Protein Name
NM_001384350.1 NP_001371279.1 alpha-lactalbumin precursor
NM_002289.3 NP_002280.1 alpha-lactalbumin precursor

LALBA Protein Structure

Lys

Lys: C-type lysozyme/alpha-lactalbumin family (20 - 139)

  • 0
  • 100
  • 142 a.a.
Protein Preferred Names Protein Names

alpha-lactalbumin

  • lactose synthase B protein

Recombinant LALBA Proteins

Cat. No. Product Name Accession Purity
HY-P70229 LALBA Protein, Human (HEK293, His) P00709 (K20-L142) ≥ 95%, as determined by reducing SDS-PAGE.

LALBA Antibodies

Cat. No. Product Name Application Reactivity
HY-P85667 LALBA Antibody (YA5359) WB, IHC-P, ICC/IF, Human

Related Diseases

Diseases Alias
Milk Allergy

  • Milk Allergic Reaction

  • Milk Hypersensitivity

  • Allergy Milk
Skin Papilloma

  • Cutaneous Papilloma

  • Papilloma Of Skin

  • Papilloma Skin
Cow Milk Allergy

  • Bos Taurus Milk Allergy

  • Cow'S Milk Protein Sensitivity
Mastitis

  • Breast Inflammation

  • Inflammatory Breast Disease

  • Inflammatory Disease Of Breast

  • Inflammation Of Non-Human Mammary Gland

  • Inflammatory Disorder Of Breast

  • Mastitis Nos

  • Acute Mastitis Nos

  • Acute Nonpuerperal Mastitis

  • Nonpuerperal Mastitis Nos

  • Subacute Mastitis Nos
Breast Cystic Hypersecretory Carcinoma

  • Cystic Hypersecretory Carcinoma Of The Breast

  • Cystic Hypersecretory Duct Carcinoma Of The Breast
Lipid-Rich Carcinoma
Glycogen-Rich Carcinoma

  • Doid:0081028
Egg Allergy

  • Allergy To Eggs

  • Allergies Egg

  • Egg Hypersensitivity
Pregnancy Adenoma

  • Lactating Adenoma
Epilepsy, Juvenile Absence 1

  • Epilepsy, Juvenile Absence, Susceptibility To, 1

  • EJA1

  • JAE1

  • Juvenile Absence Epilepsy 1

  • Susceptibility To Juvenile Absence Epilepsy 1

  • Epilepsy, Juvenile Absence, Susceptibility To, Type 1

  • Absence Epilepsy
Cystic Basal Cell Carcinoma

  • Skin Cystic Basal Cell Carcinoma
Adenoid Basal Cell Carcinoma

  • Skin Adenoid Basal Cell Carcinoma

  • Basal Cell Carcinoma - Adenoid
Lactose Intolerance

  • Lactose Malabsorption

  • Lm - Lactose Malabsorption

  • Alactasia

  • Dairy Product Intolerance

  • Hypolactasia

  • Milk Sugar Intolerance

  • Cow Milk Enteropathy

  • Intolerance Or Malabsorption Of Lactose

  • Lm - [Lactose Malabsorption]

  • Milk Intolerance
Fish Allergy

  • Allergy To Fish
Allergic Disease

  • Hypersensitivity

  • Allergic Hypersensitivity Disease

  • Allergic Condition

  • Allergic Reaction

  • Allergic Disposition
Food Allergy

  • Food Hypersensitivity

  • Food Allergies

  • Allergy Food

  • Food Allergen-Induced Hypersensitivity
Polyposis Syndrome, Hereditary Mixed, 2

  • HMPS2

  • Hereditary Mixed Polyposis Syndrome 2

  • Polyposis Syndrome, Mixed Hereditary 2

  • Polyposis Syndrome, Hereditary Mixed, Type 2
Celiac Disease 1

  • Celiac Disease

  • Coeliac Disease

  • Celiac Sprue

  • Celiac Disease, Susceptibility To

  • Gluten-Sensitive Enteropathy

  • Nontropical Sprue

  • Sprue

  • CELIAC1

  • Celiac Disease, Susceptibility To, 1

  • Celiac Sprue 1

  • Celiac Sprue, Susceptibility To, 1

  • Gluten-Sensitive Enteropathy 1

  • Gluten-Sensitive Enteropathy, Susceptibility To, 1

  • Idiopathic Steatorrhea

  • Cœliac Disease

  • Gluten Intolerance

  • Gluten-Induced Enteropathy

  • Gluten Enteropathy

  • Celiac Disease, Susceptibility To, Type 1

  • Childhood Celiac Disease

  • Coeliac Rickets

  • Gee Disease

  • Gee-Herter Disease

  • Heubner-Herter Disease

  • Idiopathic Steatorrhoea

  • Thaysen'S Disease

  • Herter Gee Syndrome
Perinatal Necrotizing Enterocolitis

  • Necrotizing Enterocolitis

  • Enterocolitis Necrotizing

  • Enterocolitis, Necrotizing

  • Necrotizing Enterocolitis In Fetus Or Newborn

  • Perinatal Necrotising Enterocolitis

  • Pseudomembranous Enterocolitis In Newborn

  • Nec
Dermatitis, Atopic

  • Atopic Dermatitis

  • Atopic Eczema

  • Dermatitis, Atopic, Susceptibility To, 1

  • Atod

  • Eczema, Atopic

  • Dermatitis, Atopic 1

  • Allergic Dermatitis

  • Atopic Neurodermatitis

  • Besnier'S Prurigo

  • Dermatitis, Atopic, 1

  • Dermatitis Atopic

  • Eczema

  • Besnier Prurigo
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07496 LALBA Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21621 Lalba Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28139 Lalba Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta LALBA VGNC VGNC:74224
Rattus norvegicus LALBA RGD RGD:2987
Canis familiaris LALBA VGNC VGNC:42563
Felis catus LALBA VGNC VGNC:68002
Bos taurus LALBA VGNC VGNC:30768
Mus musculus LALBA MGD MGI:96742
Others LALBA NCBI