DEFB103A - defensin beta 103A Gene

Homo sapiens

Also known as BD-3; HBD3; HBP3; DEFB3; HBP-3; DEFB-3; DEFB103

Gene ID: 414325 | Gene type: protein coding

About DEFB103A

This gene has 1 transcript (splice variant), 1 gene allele, 94 orthologues and 1 paralogue. Low expression observed in reference dataset.

Summary

Defensins form a family of microbicidal and cytotoxic Peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 103, an Antibiotic peptide which is induced by bacteria and interferon gamma, and which displays antimicrobial activity against S. aureus, S. pyogenes, P. aeruginosa, E. coli, and C. albicans. [provided by RefSeq, Oct 2014]

DEFB103A Products(1)

mRNA	Protein	Name
NM_001081551.4	NP_001075020.1	beta-defensin 103 precursor

DEFB103A Protein Structure

Defensin_beta

0
67 a.a.

Protein Preferred Names

Protein Names

beta-defensin 103

beta-defensin 3

Recombinant DEFB103A Proteins

Cat. No.	Product Name	Accession	Purity
HY-P7137	BD-3 Protein, Human	P81534 (G23-K67)	≥95%

Related Diseases

Diseases

Alias

Ileitis

Crohn'S Ileitis

Cardiomyopathy, Familial Hypertrophic, 12

Hypertrophic Cardiomyopathy 12	CMH12
Cardiomyopathy, Hypertrophic, 12	Cardiomyopathy Familial Hypertrophic 12
Cardiomyopathy, Familial Hypertrophic 12	Cardiomyopathy, Hypertrophic, Familial, Type 12

Cardiomyopathy, Familial Hypertrophic, 6

Hypertrophic Cardiomyopathy 6	CMH6
Familial Hypertrophic Cardiomyopathy With Wolff-Parkinson-White Syndrome	Cardiomyopathy, Familial Hypertrophic 6
Cardiomyopathy, Hypertrophic 6	Cardiomyopathy, Hypertrophic, Familial, Type 6

Eczema Herpeticum

Herpes Simplex Dermatitis	Herpes Simplex Eyelid Dermatitis
Kaposi Varicelliform Eruption	Herpes Simplex Dermatitis Of Eyelid
Herpes Simplex Virus Dermatitis	Herpes Simplex Virus Eyelid Dermatitis

Denture Stomatitis

Stomatitis, Denture

Denture Sore Mouth

Crohn'S Colitis

Crohn Disease

Oral Candidiasis

Thrush	Candidiasis Of Mouth
Oral Moniliasis	Thrush, Oral
Candidiasis, Oral	Oral Thrush
Candidiasis	Equine Thrush

Vaginal Disease

Vaginal Diseases

Chronic Mucocutaneous Candidiasis

Candidiasis, Chronic Mucocutaneous	Cmc
Candidiasis Chronic Mucocutaneous

Dermatitis, Atopic

Atopic Dermatitis	Atopic Eczema
Dermatitis, Atopic, Susceptibility To, 1	Atod
Eczema, Atopic	Dermatitis, Atopic 1
Allergic Dermatitis	Atopic Neurodermatitis
Besnier'S Prurigo	Dermatitis, Atopic, 1
Dermatitis Atopic	Eczema
Besnier Prurigo

Skin Disease

Skin Diseases	Genodermatosis
Abnormality Of The Skin	Skin Diseases, Genetic
Skin And Subcutaneous Tissue Disease	Dermatologic Disorders

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS03679	DEFB103A Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	DEFB103A	MGD	MGI:2675345
Rattus norvegicus	DEFB103A	RGD	RGD:1561378

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