SIRT3 - sirtuin 3 Gene

Canis lupus familiaris (sub-species: familiaris)

Gene ID: 475933 | Gene type: protein coding

About SIRT3

Primary_assembly 18: 25,895,722-25,914,795 reverse strand.ROS_Cfam_1.0:CM025117.1

This gene has 2 transcripts (splice variants), 197 orthologues and 6 paralogues.

mRNA	Protein	Name
XM_038423975.1	XP_038279903.1	NAD-dependent protein deacetylase sirtuin-3, mitochondrial isoform X7
XM_038423971.1	XP_038279899.1	NAD-dependent protein deacetylase sirtuin-3, mitochondrial isoform X4
XM_038423968.1	XP_038279896.1	NAD-dependent protein deacetylase sirtuin-3, mitochondrial isoform X3
XM_038423969.1	XP_038279897.1	NAD-dependent protein deacetylase sirtuin-3, mitochondrial isoform X4
XM_038423967.1	XP_038279895.1	NAD-dependent protein deacetylase sirtuin-3, mitochondrial isoform X2
XM_038423970.1	XP_038279898.1	NAD-dependent protein deacetylase sirtuin-3, mitochondrial isoform X4
XM_038423976.1	XP_038279904.1	NAD-dependent protein deacetylase sirtuin-3, mitochondrial isoform X6
XM_038423966.1	XP_038279894.1	NAD-dependent protein deacetylase sirtuin-3, mitochondrial isoform X1
XM_038423973.1	XP_038279901.1	NAD-dependent protein deacetylase sirtuin-3, mitochondrial isoform X4
XM_038423972.1	XP_038279900.1	NAD-dependent protein deacetylase sirtuin-3, mitochondrial isoform X4
XM_038423974.1	XP_038279902.1	NAD-dependent protein deacetylase sirtuin-3, mitochondrial isoform X5

SIRT1

Protein Preferred Names

Protein Names

NAD-dependent protein deacetylase sirtuin-3, mitochondrial

Approval

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-B0130	Perindopril		99.85%	Yes
HY-B0130A	Perindopril erbumine		99.98%	Yes

Clinical Phase

Bioactive Molecules (4)

Cat. No.	Product Name	Effect	Purity	Phase
HY-123033A	Nicotinamide riboside chloride	Activator	99.90%	Phase 4
HY-123033C	Nicotinamide riboside malate	Activator	98.04%	Phase 4
HY-123033B	Nicotinamide riboside tartrate	Activator	98.07%	Phase 4
HY-123033	Nicotinamide riboside	Activator	/	Phase 4

Pre-clinical Phase

Bioactive Molecules (35)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-108331	3-TYP	Inhibitor	99.96%	Unkown
HY-100578	AGK2	Inhibitor	99.43%	Unkown
HY-113402	Gamma-glutamylcysteine	Activator	98.53%	Unkown
HY-158426	2-APQC	Agonist	99.70%	Unkown
HY-15510	Tenovin-6	Inhibitor	98.00%	Unkown
HY-N1511	Ganoderic acid D	Activator	99.89%	Unkown
HY-N2110	Phellopterin	Agonist	99.94%	Unkown
HY-119575	Tetramethyluric acid	Activator	99.63%	Unkown
HY-136199	SIRT1-IN-1	Inhibitor	98.15%	Unkown
HY-16616	SIRT-IN-2	Inhibitor	98.08%	Unkown
HY-N2673	5-Heptadecylresorcinol	Activator	99.83%	Unkown
HY-15510B	Tenovin-6 Hydrochloride	Inhibitor	98.88%	Unkown
HY-16605	SIRT6-IN-6	Inhibitor	98.59%	Unkown
HY-163987	SIRT3 activator 2	Activator	98.94%	Unkown
HY-173572	SKLB-11A	Agonist	99.40%	Unkown
HY-124113	4'-Bromo-resveratrol	Inhibitor	99.94%	Unkown
HY-161920	SIRT3-IN-1	Inhibitor	98.47%	Unkown
HY-16615	SIRT-IN-1	Inhibitor	98.14%	Unkown
HY-111329	JGB1741	Inhibitor	99.37%	Unkown
HY-151519	SIRT2-IN-9	Inhibitor	99.45%	Unkown
HY-136855	MitoPBN	Modulator	95.00%	Unkown
HY-19339	Tenovin-3	Degrader	98.0%	Unkown
HY-150727	SIRT5 inhibitor 4	Inhibitor	98.37%	Unkown
HY-118343	AC-93253	Inhibitor	99.3%	Unkown
HY-P3364A	Ac-QPKK(Ac)-AMC acetate	Substrate	/	Unkown
HY-111303	CHIC35	Inhibitor	/	Unkown
HY-155784	SPC-180002	Inhibitor	/	Unkown
HY-160944	hsa62	Inhibitor	/	Unkown
HY-160617	SIRT2-IN-14	Inhibitor	/	Unkown
HY-170402	SIRT6-IN-4	Inhibitor	/	Unkown
HY-114906	SIRT1/2/3-IN-2	Inhibitor	/	Unkown
HY-124946	C1A	Inhibitor	/	Unkown
HY-146013	Sirt1/2-IN-1	Inhibitor	/	Unkown
HY-118109	SIRT3-IN-2	Inhibitor	/	Unkown
HY-W109401	SIRT-IN-6	Inhibitor	/	Unkown

Species	Symbol	Source	ID
Homo sapiens	SIRT3	NCBI	NCBI:23410
Mus musculus	SIRT3	NCBI	NCBI:64384

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