SIRT3 - sirtuin 3 Gene

Species: Canis lupus familiaris (sub-species: familiaris)

Gene Type: protein coding
Gene ID: 475933

About SIRT3

Primary_assembly 18: 25,895,722-25,914,795 reverse strand.ROS_Cfam_1.0:CM025117.1

This gene has 2 transcripts (splice variants), 197 orthologues and 6 paralogues.

SIRT3 Products (11)

mRNA Protein Name
XM_038423975.1 XP_038279903.1 NAD-dependent protein deacetylase sirtuin-3, mitochondrial isoform X7
XM_038423971.1 XP_038279899.1 NAD-dependent protein deacetylase sirtuin-3, mitochondrial isoform X4
XM_038423968.1 XP_038279896.1 NAD-dependent protein deacetylase sirtuin-3, mitochondrial isoform X3
XM_038423969.1 XP_038279897.1 NAD-dependent protein deacetylase sirtuin-3, mitochondrial isoform X4
XM_038423967.1 XP_038279895.1 NAD-dependent protein deacetylase sirtuin-3, mitochondrial isoform X2
XM_038423970.1 XP_038279898.1 NAD-dependent protein deacetylase sirtuin-3, mitochondrial isoform X4
XM_038423976.1 XP_038279904.1 NAD-dependent protein deacetylase sirtuin-3, mitochondrial isoform X6
XM_038423966.1 XP_038279894.1 NAD-dependent protein deacetylase sirtuin-3, mitochondrial isoform X1
XM_038423973.1 XP_038279901.1 NAD-dependent protein deacetylase sirtuin-3, mitochondrial isoform X4
XM_038423972.1 XP_038279900.1 NAD-dependent protein deacetylase sirtuin-3, mitochondrial isoform X4
XM_038423974.1 XP_038279902.1 NAD-dependent protein deacetylase sirtuin-3, mitochondrial isoform X5

SIRT3 Protein Structure

SIRT1

SIRT1: cd01408 (112 - 347)

  • 0
  • 100
  • 200
  • 300
  • 374 a.a.
Protein Preferred Names Protein Names

NAD-dependent protein deacetylase sirtuin-3, mitochondrial

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B0130 Perindopril 99.85% Yes
HY-B0130A Perindopril erbumine 99.98% Yes

Clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Phase
HY-123033A Nicotinamide riboside chloride Activator 99.90% Phase 4
HY-123033C Nicotinamide riboside malate Activator 98.04% Phase 4
HY-123033B Nicotinamide riboside tartrate Activator 98.07% Phase 4
HY-123033 Nicotinamide riboside Activator / Phase 4

Pre-clinical Phase

Bioactive Molecules (36)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-108331 3-TYP Inhibitor 99.90% Unkown
HY-113402 Gamma-glutamylcysteine Activator 98.53% Unkown
HY-100578 AGK2 Inhibitor 99.43% Unkown
HY-158426 2-APQC Agonist 99.70% Unkown
HY-15510 Tenovin-6 Inhibitor 98.00% Unkown
HY-N1511 Ganoderic acid D Activator 99.89% Unkown
HY-N2110 Phellopterin Agonist 99.94% Unkown
HY-119575 Tetramethyluric acid Activator 99.63% Unkown
HY-16616 SIRT-IN-2 Inhibitor 98.08% Unkown
HY-136199 SIRT1-IN-1 Inhibitor 98.15% Unkown
HY-N2673 5-Heptadecylresorcinol Activator 99.83% Unkown
HY-16605 SIRT6-IN-6 Inhibitor 98.59% Unkown
HY-163987 SIRT3 activator 2 Activator 98.94% Unkown
HY-15510B Tenovin-6 Hydrochloride Inhibitor 98.88% Unkown
HY-173572 SKLB-11A Agonist 99.40% Unkown
HY-161920 SIRT3-IN-1 Inhibitor 98.47% Unkown
HY-124113 4'-Bromo-resveratrol Inhibitor 99.94% Unkown
HY-16615 SIRT-IN-1 Inhibitor 98.14% Unkown
HY-111329 JGB1741 Inhibitor 99.37% Unkown
HY-19339 Tenovin-3 Degrader 98.0% Unkown
HY-150727 SIRT5 inhibitor 4 Inhibitor 98.37% Unkown
HY-136855 MitoPBN Modulator 95.00% Unkown
HY-P3364A Ac-QPKK(Ac)-AMC acetate Substrate 99.38% Unkown
HY-151519 SIRT2-IN-9 Inhibitor 99.45% Unkown
HY-118343 AC-93253 Inhibitor 99.3% Unkown
HY-111303 CHIC35 Inhibitor / Unkown
HY-170402 SIRT6-IN-4 Inhibitor / Unkown
HY-155784 SPC-180002 Inhibitor / Unkown
HY-124946 C1A Inhibitor / Unkown
HY-146013 Sirt1/2-IN-1 Inhibitor / Unkown
HY-114906 SIRT1/2/3-IN-2 Inhibitor / Unkown
HY-160944 hsa62 Inhibitor / Unkown
HY-160617 SIRT2-IN-14 Inhibitor / Unkown
HY-184173 OXPHOS-IN-3 Inhibitor / Unkown
HY-118109 SIRT3-IN-2 Inhibitor / Unkown
HY-W109401 SIRT-IN-6 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens SIRT3 NCBI NCBI:23410