SIRT1/2/3-IN-2
SIRT1/2/3-IN-2 (compound 9) is a potent SIRT inhibitor, with inhibition rates of 27%, 72%, and 71% targeting SIRT1, SIRT2, and SIRT3, respectively, at 200 μM. SIRT3 is a potential tumor suppressor or promoter, and its increased transcription may be associated with lymph node-positive breast cancer and oral squamous cell carcinoma.
For research use only. We do not sell to patients.
- CAS No.: 388086-13-3
- Formula: C21H14Cl2N2O2
- Molecular Weight:397.25
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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SIRT1 |
SIRT2 |
SIRT3 |
Chemical Information
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CAS No. 388086-13-3
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Molecular Weight 397.25
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Formula C21H14Cl2N2O2
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SMILES
ClC1=C(C2=NC3=CC(NC(CC4=CC=CC=C4)=O)=CC=C3O2)C=CC(Cl)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SIRT1/2/3-IN-2 Related Classifications
HY-114906 Related Classifications
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