Lpar2 - lysophosphatidic acid receptor 2 Gene

Rattus norvegicus

Also known as Edg4; RGD1561336

Gene ID: 498609 | Gene type: protein coding

About Lpar2

Primary_assembly 16: 19,595,655-19,599,998 reverse strand.mRatBN7.2:CM026989.1

This gene has 1 transcript (splice variant), 270 orthologues and 18 paralogues. Biased expression in Adrenal (RPKM 44.7), Kidney (RPKM 38.9) and 6 other tissues.

Summary

Predicted to enable G protein-coupled receptor activity and PDZ domain binding activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway and regulation of metabolic process. Predicted to act upstream of or within G protein-coupled receptor signaling pathway; positive regulation of MAPK cascade; and positive regulation of Rho protein signal transduction. Predicted to be located in cell surface. Predicted to be active in cytoplasm; glutamatergic synapse; and plasma membrane. Predicted to be integral component of presynaptic active zone membrane. Predicted to colocalize with endocytic vesicle. Orthologous to human LPAR2 (lysophosphatidic acid receptor 2). [provided by Alliance of Genome Resources, Apr 2022]

Lpar2 Products(1)

mRNA	Protein	Name
NM_001109109.2	NP_001102579.2	lysophosphatidic acid receptor 2

Lpar2 Protein Structure

7tm_GPCRs

0
100
200
300
348 a.a.

Protein Preferred Names

Protein Names

lysophosphatidic acid receptor 2

endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor 4

pre-B-cell leukemia transcription factor 4

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-107616	H2L5186303	Antagonist	98.72%	Unkown
HY-100676	GRI977143	Agonist	99.84%	Unkown
HY-118539	NSC12404	Agonist	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Lpar2	NCBI	NCBI:9170

Name
Email *

	Sorry, but the email address you supplied was invalid.