Lpar2 - lysophosphatidic acid receptor 2 Gene
Also Known as Edg4; RGD1561336
Species: Rattus norvegicus
About Lpar2
This gene has 1 transcript (splice variant), 270 orthologues and 18 paralogues. Biased expression in Adrenal (RPKM 44.7), Kidney (RPKM 38.9) and 6 other tissues.
Summary
Predicted to enable G protein-coupled receptor activity and PDZ domain binding activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway and regulation of metabolic process. Predicted to act upstream of or within G protein-coupled receptor signaling pathway; positive regulation of MAPK cascade; and positive regulation of Rho protein signal transduction. Predicted to be located in cell surface. Predicted to be active in cytoplasm; glutamatergic synapse; and plasma membrane. Predicted to be integral component of presynaptic active zone membrane. Predicted to colocalize with endocytic vesicle. Orthologous to human LPAR2 (lysophosphatidic acid receptor 2). [provided by Alliance of Genome Resources, Apr 2022]
Lpar2 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_001109109.2 | NP_001102579.2 | lysophosphatidic acid receptor 2 |
Lpar2 Protein Structure
7tm_GPCRs: cl28897 (29 - 302)
7tm_GPCRs: cd14964 (31 - 55)
7tm_GPCRs: cd14964 (64 - 85)
7tm_GPCRs: cd14964 (101 - 123)
7tm_GPCRs: cd14964 (145 - 161)
7tm_GPCRs: cd14964 (182 - 205)
7tm_GPCRs: cd14964 (236 - 258)
7tm_GPCRs: cd14964 (270 - 295)
- 0
- 100
- 200
- 300
- 348 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
lysophosphatidic acid receptor 2 |
|