BrP-LPA sodium
BrP-LPA sodium is a pan-opposite agent for lysophosphatidic acid (LPA). It has antagonistic activity against LPA1 (IC50 = 4520 nM), LPA2 (IC50 = 468 nM), LPA3, and LPA4. BrP-LPA sodium also has partial agonistic activity for LPA5, with its EC50 being 1282 nM. BrP-LPA sodium has ATX inhibitory activity. BrP-LPA sodium effectively inhibits the migration and invasion of breast cancer cells. BrP-LPA sodium achieves tumor regression and anti-angiogenesis in mice breast cancer xenograft model. BrP-LPA sodium can be used for the study of breast cancer.
For research use only. We do not sell to patients.
- CAS No.: 944265-88-7
- Formula: C20H39BrNaO6P
- Molecular Weight:509.39
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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LPA1 Receptor |
LPA2 Receptor |
LPA3 Receptor |
LPA5 Receptor |
Autotaxin |
Chemical Information
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CAS No. 944265-88-7
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Molecular Weight 509.39
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Formula C20H39BrNaO6P
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SMILES
O=P(O)(O[Na])C(Br)C[C@H](O)COC(CCCCCCCCCCCCCCC)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
BrP-LPA sodium Related Classifications
HY-148291 Related Classifications
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